Overview

  • Product name
  • Description
    Rabbit polyclonal to GALNS
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Pig
  • Immunogen

    Recombinant fragment corresponding to Human GALNS aa 352-522 (C terminal).
    Database link: P34059

  • Positive control
    • MCF7, HT29, 293T, mouse kidney, mouse brain and mouse intestine extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab187516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 58 kDa.
IHC-P 1/50 - 1/200.

Target

  • Relevance
    GALNS (N-acetylgalactosamine-6-sulfatase) is a lysosomal exohydrolase which catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.
  • Cellular localization
    Lysosome
  • Database links
  • Alternative names
    • Chondroitinase antibody
    • Chondroitinsulfatase antibody
    • FLJ00319 antibody
    • FLJ17434 antibody
    • FLJ42844 antibody
    • FLJ98217 antibody
    • Galactosamine (N acetyl) 6 sulfate sulfatase antibody
    • Galactose 6 sulfate sulfatase antibody
    • GALNAC6S antibody
    • GalNAc6S sulfatase antibody
    • GALNS6 antibody
    • GAS antibody
    • mFLJ00319 antibody
    • MPS4A antibody
    • N acetylgalactosamine 6 sulfatase antibody
    • N acetylgalactosamine 6 sulfate sulfatase antibody
    see all

Images

  • All lanes : Anti-GALNS antibody (ab187516) at 1/500 dilution

    Lane 1 : MCF7 cell extract
    Lane 2 : HT29 cell extract
    Lane 3 : 293T cell extract
    Lane 4 : Mouse kidney extract
    Lane 5 : Mouse brain extract
    Lane 6 : Mouse intestine extract


    Predicted band size : 58 kDa

References

ab187516 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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