Anti-GALNT10 antibody (ab106471)

Overview

• Product nameAnti-GALNT10 antibody
  See all GALNT10 primary antibodies
• Description
  Rabbit polyclonal to GALNT10
• Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  An 18 amino acid synthetic peptide near the C terminus of Human GALNT10 (NP_938080).

• Positive control
  • SK-N-SH cell lysate; Human brain tissue

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Golgi

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• FunctionCatalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates.
• Tissue specificityWidely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues.
• PathwayProtein modification; protein glycosylation.
• Sequence similaritiesBelongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
  Contains 1 ricin B-type lectin domain.
• DomainThere are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
  The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
• Cellular localizationGolgi apparatus membrane.

• Target information above from: UniProt accession Q86SR1 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 55568 Human
  • Entrez Gene: 171212 Mouse
  • Entrez Gene: 170501 Rat
  • Omim: 608043 Human
  • SwissProt: Q86SR1 Human
  • SwissProt: Q6P9S7 Mouse
  • SwissProt: Q925R7 Rat
  • Unigene: 631797 Human

  • Unigene: 726056 Human
  • Unigene: 271670 Mouse
  • Unigene: 60224 Rat

  see all
• Alternative names
  • DKFZp586H0623 antibody
  • FLJ00205 antibody
  • FLJ11715 antibody

  • GalNAc T10 antibody
  • GalNAc transferase 10 antibody
  • GalNAc-T10 antibody
  • GalNAcT10 antibody
  • GALNT10 antibody
  • GLT10_HUMAN antibody
  • Polypeptide GalNAc transferase 10 antibody
  • Polypeptide N-acetylgalactosaminyltransferase 10 antibody
  • pp GalNAc T10 antibody
  • pp GaNTase 10 antibody
  • pp-GaNTase 10 antibody
  • ppGalNAcT10 antibody
  • ppGaNTase 10 antibody
  • Protein UDP acetylgalactosaminyltransferase 10 antibody
  • Protein-UDP acetylgalactosaminyltransferase 10 antibody
  • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 10 antibody
  • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 10 antibody
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10 antibody
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) antibody

  see all