Overview

  • Product name
  • Description
    Mouse polyclonal to GALNT10
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-603 of Human GALNT10 (Q86SR1).

  • Positive control
    • GALNT10 transfected 293T cell line lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab168400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa.

Target

  • Function
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates.
  • Tissue specificity
    Widely expressed. Expressed at high level in small intestine, and at intermediate levels in stomach, pancreas, ovary, thyroid gland and spleen. Weakly expressed in other tissues.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • Domain
    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp586H0623 antibody
    • FLJ00205 antibody
    • FLJ11715 antibody
    • GalNAc T10 antibody
    • GalNAc transferase 10 antibody
    • GalNAc-T10 antibody
    • GalNAcT10 antibody
    • GALNT10 antibody
    • GLT10_HUMAN antibody
    • Polypeptide GalNAc transferase 10 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 10 antibody
    • pp GalNAc T10 antibody
    • pp GaNTase 10 antibody
    • pp-GaNTase 10 antibody
    • ppGalNAcT10 antibody
    • ppGaNTase 10 antibody
    • Protein UDP acetylgalactosaminyltransferase 10 antibody
    • Protein-UDP acetylgalactosaminyltransferase 10 antibody
    • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 10 antibody
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 10 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) antibody
    see all

Images

  • All lanes : Anti-GALNT10 antibody (ab168400) at 1 µg/ml

    Lane 1 : GALNT10 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate


    Predicted band size : 69 kDa

References

ab168400 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab168400.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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