Overview

  • Product name
  • Description
    Rabbit polyclonal to GALNT11
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 98-147 (LGMIFNERDQ ELRDLGYQKH AFNMLISNRL GYHRDVPDTR NAECRRKSYP) of Rat GALNT11 (NP_955425).

  • Positive control
    • Rat heart lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Constituents: PBS, 2% Sucrose
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab110861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin.
  • Tissue specificity
    Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in glomeruli.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • Domain
    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • A430075I06Rik antibody
    • AI648252 antibody
    • E430002F06Rik antibody
    • FLJ21634 antibody
    • GalNAc Transferase 11 antibody
    • GalNAc-T11 antibody
    • GalNAcT11 antibody
    • GALNT11 antibody
    • GLT11_HUMAN antibody
    • MGC71630 antibody
    • Polypeptide GalNAc transferase 11 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 11 antibody
    • pp-GaNTase 11 antibody
    • Protein-UDP acetylgalactosaminyltransferase 11 antibody
    • tcag7.1057 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) antibody
    see all

Anti-GALNT11 antibody images

  • Anti-GALNT11 antibody (ab110861) at 1 µg/ml + Rat heart lysate at 10 µg

    Predicted band size : 69 kDa

References for Anti-GALNT11 antibody (ab110861)

ab110861 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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