• Product nameAnti-GALNT3 antibody
    See all GALNT3 primary antibodies
  • Description
    Mouse polyclonal to GALNT3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Fragment (aa 1-141) of the human full length protein


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab67590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 73 kDa.


  • FunctionCatalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis.
  • Tissue specificityExpressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney.
  • PathwayProtein modification; protein glycosylation.
  • Involvement in diseaseDefects in GALNT3 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC) [MIM:211900]. HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Some patients manifest recurrent, transient, painful swellings of the long bones associated with the radiographic findings of periosteal reaction and cortical hyperostosis and absence of skin involvement.
  • Sequence similaritiesBelongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • DomainThere are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • Cellular localizationGolgi apparatus > Golgi stack membrane. Resides preferentially in the trans and medial parts of the Golgi stack.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686C10199 antibody
    • EC antibody
    • GalNAc T3 antibody
    • GalNAc transferase 3 antibody
    • GalNAc-T3 antibody
    • GalNAcT3 antibody
    • GALNT3 antibody
    • GALT3_HUMAN antibody
    • HFTC antibody
    • HHS antibody
    • MGC61909 antibody
    • OTTHUMP00000204915 antibody
    • OTTHUMP00000204919 antibody
    • Polypeptide GalNAc transferase 3 antibody
    • Polypeptide GalNAc transferase T3 antibody
    • Polypeptide N acetylgalactosaminyltransferase 3 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 3 antibody
    • pp-GaNTase 3 antibody
    • ppGaNTase 3 antibody
    • Protein UDP acetylgalactosaminyltransferase 3 antibody
    • Protein-UDP acetylgalactosaminyltransferase 3 antibody
    • RP23-306G16.2 antibody
    • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 3 antibody
    • UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 3 (GalNAc T3) antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 antibody
    see all

Anti-GALNT3 antibody images

  • All lanes : Anti-GALNT3 antibody (ab67590) at 1/500 dilution

    Lane 1 : GALNT3 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Goat Anti-Mouse IgG (H&L)-HRP conjugated secondary antibody at 1/2500 dilution

    Predicted band size : 73 kDa
    Observed band size : 14 kDa (why is the actual band size different from the predicted?)

References for Anti-GALNT3 antibody (ab67590)

ab67590 has not yet been referenced specifically in any publications.

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