Overview

  • Product nameAnti-GALNT4 antibody
    See all GALNT4 primary antibodies
  • Description
    Rabbit polyclonal to GALNT4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region betweenn N terminal amino acids 100-128 of Human GALNT4 (NP_003765.2), conjugated to KLH.

  • Positive control
    • Hela cell line lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab107497 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab107497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 67 kDa.

Target

  • FunctionCatalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG.
  • Tissue specificityUbiquitous. Highly expressed in mucous cells.
  • PathwayProtein modification; protein glycosylation.
  • Sequence similaritiesBelongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • DomainThere are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain directs the glycopeptide specificity. It is required in the glycopeptide specificity of enzyme activity but not for activity with naked peptide substrates, suggesting that it triggers the catalytic domain to act on GalNAc-glycopeptide substrates.
  • Cellular localizationGolgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 2.4.1.41 antibody
    • GALNAC T4 antibody
    • GalNAc transferase 4 antibody
    • GalNAc-T4 antibody
    • GalNAcT4 antibody
    • GALNT4 antibody
    • GALT4_HUMAN antibody
    • N-acetylgalactosaminyltransferase 4 (GalNAc-T4) antibody
    • Polypeptide GalNAc transferase 4 antibody
    • Polypeptide N-acetylgalactosaminyltransferase 4 antibody
    • pp GaNTase 4 antibody
    • pp-GaNTase 4 antibody
    • Protein UDP acetylgalactosaminyltransferase 4 antibody
    • Protein-UDP acetylgalactosaminyltransferase 4 antibody
    • UDP GalNAc:polypeptide N-acetylgalactosaminyltransferase 4 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide antibody
    see all

Anti-GALNT4 antibody images

  • Anti-GALNT4 antibody (ab107497) at 1/100 dilution + Hela cell line lysates at 35 µg

    Predicted band size : 67 kDa

References for Anti-GALNT4 antibody (ab107497)

ab107497 has not yet been referenced specifically in any publications.

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