Overview

  • Product nameAnti-GALNTL6 antibody
    See all GALNTL6 primary antibodies
  • Description
    Rabbit polyclonal to GALNTL6
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence corresponding to amino acids 33-114 (DKHLVKSAEP GEQQTFPLGL GDGQFYSWTD GLRRKDWHDY ESIQKEAMRS GKGEHGKPYP LTEEDHDDSA YRENGFNIFV SN) of Human GALNTL6.

  • Positive control
    • Human Placenta tissue; RT-4 and U-251 MG cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab122149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionCatalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
  • PathwayProtein modification; protein glycosylation.
  • Sequence similaritiesBelongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.
  • DomainThere are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
  • Cellular localizationGolgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 2.4.1.41 antibody
    • GalNAc transferase 17 antibody
    • GalNAc-T17 antibody
    • GALNACT20 antibody
    • GALNTL6 antibody
    • GaNTase 17 antibody
    • GLTL6_HUMAN antibody
    • MGC44629 antibody
    • OTTHUMP00000219021 antibody
    • OTTHUMP00000219023 antibody
    • Polypeptide GalNAc transferase 17 antibody
    • Polypeptide N-acetylgalactosaminyltransferase-like 6 antibody
    • polypeptide N-acetylgalactosaminyltransferase-like 6 UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 20 antibody
    • pp-GaNTase 17 antibody
    • Protein-UDP acetylgalactosaminyltransferase 17 antibody
    • Putative polypeptide N-acetylgalactosaminyltransferase 17 antibody
    • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17 antibody
    • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like antibody
    see all

Anti-GALNTL6 antibody images

  • All lanes : Anti-GALNTL6 antibody (ab122149) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique
  • ab122149, at 1/135, staining GALNTL6 in paraffin-embedded Human placenta tissue by Immunohistochemistry.

References for Anti-GALNTL6 antibody (ab122149)

ab122149 has not yet been referenced specifically in any publications.

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