This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

Applications

  • Application notes
    Peptide ELISA: antibody detection limit dilution 1:64,000.
    Western Blot: Preliminary experiments in human brain and skin lysates gave no specific signal but low background, at antibody concentration up to 1µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, may have vasoactive properties and serve as a marker for neuroblastic tumors. Isoform 2 exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effect which does not appear to be mediated via GALR1 or GALR2.
    • Cellular localization
      Secreted
    • Database links
    • Alternative names
      • Alarin antibody
      • Alarin splice variant antibody
      • Galanin like peptide antibody
      • Galanin like peptide precursor protein antibody
      • GALP precursor protein antibody
      see all

    References

    ab78601 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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