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Product Name 

gamma Adaptin antibody [IMD-113]

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal [IMD-113] to gamma Adaptin

Immunogen 

AP-1 adaptor from bovine brain.

Reacts with 

Hu, Rat

Predicted to react 
(species key)

Ms, Cow
(Due to sequence homology)

Tested applications 
(see key)

WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 91 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Research areas 

Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Adapters

Relevance 

Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta, beta prime and gamma adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.

 

Alternative names gamma Adaptin antibody [IMD-113] (ab82246)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

507677    (Cow)
164    (Human)
11765    (Mouse)
171494    (Rat)

GeneCard

    

GC16M071500    (Human)

Omim

    

603533    (Human)

SwissProt

    

O43747    (Human)
P22892    (Mouse)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

IMD-113

Isotype 

IgG2b

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 1.2% Sodium acetate, 2mg/ml BSA

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

ab82246 is purified using goat anti-mouse IgG affinity chromatography.

Form 

Liquid

Concentration 

0.100 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this gamma Adaptin antibody [IMD-113] is on this datasheet. But please do contact us if you would like any reassurance!


 

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