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AbcamBiochemicals (Asc-307)

γ-DGG (γ-D-glutamylglycine) (ab120307)

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Overview

  • Product nameγ-DGG (γ-D-glutamylglycine)
  • Description
    Ionotropic glutamate antagonist. Low affinity AMPA antagonist.
  • Alternative names
    γ-D-glutamylglycine
  • Biological descriptionIonotropic glutamate receptor antagonist that has been used as a rapidly dissociating, low affinity competitive antagonist at AMPA receptors.
  • Purity> 99%

    • Properties

  • Chemical name(R)-4-(carboxymethylcarbamoyl)-2-aminobutanoic acid
  • Molecular Weight204.18
  • Chemical structureChemical Structure
  • Molecular formulaC7H12N2O5
  • CAS Number6729-55-1
  • PubChem identifier6604701
  • Storage instructionsStore at +4°C (desiccating conditions).
  • Solubility overviewSoluble in water to 100 mM
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESO=C(CC[C@@H](N)C(=O)O)NCC(=O)O
  • Source

    Synthetic

  • Research Areas

    • References for γ-DGG (γ-D-glutamylglycine) (ab120307)

    This product has been referenced in:
    • Wadiche JI & Jahr CE Multivesicular release at climbing fiber-Purkinje cell synapses. Neuron 32:301-13 (2001). Read more (PubMed: 11683999) »
    • Liu G  et al. Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slices. Neuron 22:395-409 (1999). Read more (PubMed: 10069344) »
    • Watkins JC  et al. Experiments with kainate and quisqualate agonists and antagonists in relation to the sub-classification of 'non-NMDA' receptors. Adv Exp Med Biol 268:49-55 (1990). Read more (PubMed: 1963751) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"