Overview

  • Product name
    γ-Acetylenic GABA
  • Description
    Irreversible GABA transaminase inhibitor
  • Alternative names
    • 4-Amino-5-hexynoic acid
    • 4-amino-hex-5-ynoate
    • gamma-Acetylenic GABA
    • RMI 71645
  • Biological description

    Irreversible GABA transaminase inhibitor. Inhibits Tetrapyrrole biosynthesis in plants.

  • Purity
    > 98%

Properties

  • Chemical name
    4-Amino-5-hexynoic acid
  • Molecular weight
    127.14
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C6H9NO2
  • CAS Number
    57659-38-3
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Elich TD & Lagarias JC 4-amino-5-hexynoic Acid-a potent inhibitor of tetrapyrrole biosynthesis in plants. Plant Physiol 88:747-51 (1988). Read more (PubMed: 16666377) »
  • Carney IT  et al. A kinetic model for the action of the enzyme activated irreversible inhibitor 4-amino-5-hexynoic acid in vivo. Biochem Pharmacol 33:3765-9 (1984). Read more (PubMed: 6508832) »
  • Abdul-Ghani AS  et al. Effects of gamma-acetylenic GABA and gamma-vinyl GABA on synaptosomal release and uptake of GABA. Biochem Pharmacol 30:1203-9 (1981). Read more (PubMed: 7271818) »
  • Abdul-Ghani AS  et al. The action of gamma-vinyl-GABA and gamma-acetylenic-GABA on the resting and stimulated release of GABA in vivo. Brain Res 191:471-81 (1980). Read more (PubMed: 7378767) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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