Overview

  • Product nameAnti-gamma C Crystallin antibody
    See all gamma C Crystallin primary antibodies
  • Description
    Mouse monoclonal to gamma C Crystallin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: SIRSCCLIPQ TVSHRLRLYE REDHKGLMME LSEDCPSIQD RFHLSEIRSL HVLEGCWVLY ELPNYRGRQY LLRPQEYRRC QDWGAMDAKA GSLRRVVDLY , corresponding to amino acids 75-174 of Human gamma C Crystallin

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab54665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1 - 5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCrystallins are the dominant structural components of the vertebrate eye lens.
    • Involvement in diseaseDefects in CRYGC are a cause of cataract autosomal dominant (ADC) [MIM:604219]. Cataract is an opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Cataract is the most common treatable cause of visual disability in childhood.
      Defects in CRYGC are a cause of cataract Coppock-like (CCL) [MIM:604307]. A congenital pulverulent disk-like opacity involving the embryonic nucleus with many tiny white dots in the lamellar portion of the lens. It is usually bilateral and dominantly inherited.
    • Sequence similaritiesBelongs to the beta/gamma-crystallin family.
      Contains 4 beta/gamma crystallin 'Greek key' domains.
    • DomainHas a two-domain beta-structure, folded into four very similar Greek key motifs.
    • Information by UniProt
    • Database links
    • Alternative names
      • CATARACT, VARIABLE ZONULAR PULVERULENT antibody
      • CCL antibody
      • CRGC_HUMAN antibody
      • CRYG 3 antibody
      • Cryg 5 antibody
      • Cryg antibody
      • CRYG3 antibody
      • CRYGC antibody
      • Crystallin gamma 3 antibody
      • Crystallin gamma C antibody
      • Gamma C crystallin antibody
      • Gamma crystallin 2 1 antibody
      • Gamma crystallin 3 antibody
      • Gamma crystallin C antibody
      • Gamma-C-crystallin antibody
      • Gamma-crystallin 2-1 antibody
      • Gamma-crystallin 3 antibody
      • Gamma-crystallin C antibody
      • Gammab cry antibody
      • Len antibody
      see all

    Anti-gamma C Crystallin antibody images

    • Western blot against tagged recombinant protein immunogen using ab54665 gamma C Crystallin antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-gamma C Crystallin antibody (ab54665)

    ab54665 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"