Overview

  • Product nameAnti-gamma C Crystallin antibody
    See all gamma C Crystallin primary antibodies
  • Description
    Rabbit polyclonal to gamma C Crystallin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the internal amino acids 72-121 (LSDSIRSCCL IPQTVSHRLR LYEREDHKGL MMELSEDCPS IQDRFHLSEI) of Human gamma C Crystallin (NP_066269).

  • Positive control
    • OVCAR-3 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab90333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCrystallins are the dominant structural components of the vertebrate eye lens.
  • Involvement in diseaseDefects in CRYGC are a cause of cataract autosomal dominant (ADC) [MIM:604219]. Cataract is an opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Cataract is the most common treatable cause of visual disability in childhood.
    Defects in CRYGC are a cause of cataract Coppock-like (CCL) [MIM:604307]. A congenital pulverulent disk-like opacity involving the embryonic nucleus with many tiny white dots in the lamellar portion of the lens. It is usually bilateral and dominantly inherited.
  • Sequence similaritiesBelongs to the beta/gamma-crystallin family.
    Contains 4 beta/gamma crystallin 'Greek key' domains.
  • DomainHas a two-domain beta-structure, folded into four very similar Greek key motifs.
  • Information by UniProt
  • Database links
  • Alternative names
    • CATARACT, VARIABLE ZONULAR PULVERULENT antibody
    • CCL antibody
    • CRGC_HUMAN antibody
    • CRYG 3 antibody
    • Cryg 5 antibody
    • Cryg antibody
    • CRYG3 antibody
    • CRYGC antibody
    • Crystallin gamma 3 antibody
    • Crystallin gamma C antibody
    • Gamma C crystallin antibody
    • Gamma crystallin 2 1 antibody
    • Gamma crystallin 3 antibody
    • Gamma crystallin C antibody
    • Gamma-C-crystallin antibody
    • Gamma-crystallin 2-1 antibody
    • Gamma-crystallin 3 antibody
    • Gamma-crystallin C antibody
    • Gammab cry antibody
    • Len antibody
    see all

Anti-gamma C Crystallin antibody images

  • Anti-gamma C Crystallin antibody (ab90333) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 21 kDa

References for Anti-gamma C Crystallin antibody (ab90333)

ab90333 has not yet been referenced specifically in any publications.

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