Anti-gamma Catenin antibody [M111] (ab29040)

Overview

  • Product nameAnti-gamma Catenin antibody [M111]
    See all gamma Catenin primary antibodies
  • Description
    Mouse monoclonal [M111] to gamma Catenin
  • Specificityab29040 recognises gamma catenin.
  • Tested applicationsSuitable for: ELISA, WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant protein that includes amino acid residues in the C terminal region of rat gamma Catenin.

  • Positive control
    • A431 cells treated with pervanadate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 50% Glycerol, PBS, 1mg/ml BSA
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberM111
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab29040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IP
  • Application notesELISA: 1/2000.
    IP: 1-5 µl.
    WB: 1/1000 in 5% non fat milk, PBS, 0.04% Tween 20 for 1 hour at room temperature. Predicted molecular weight: 80 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCommon junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
    • Involvement in diseaseDefects in JUP are the cause of Naxos disease (NXD) [MIM:601214]. NXD is an autosomal recessive disorder combining diffuse non-epidermolytic palmoplantar keratoderma with arrhythmogenic right ventricular dysplasia/cardiomyopathy and woolly hair.
      Defects in JUP are the cause of familial arrhythmogenic right ventricular dysplasia type 12 (ARVD12) [MIM:611528]; also called arrhythmogenic right ventricular cardiomyopathy 12 (ARVC12). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
    • Sequence similaritiesBelongs to the beta-catenin family.
      Contains 9 ARM repeats.
    • Cellular localizationCell junction > adherens junction. Cell junction > desmosome. Cytoplasm > cytoskeleton. Membrane. Cytoplasmic in a soluble and membrane-associated form.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARVD 12 antibody
      • ARVD12 antibody
      • Catenin (cadherin associated protein), gamma 80kDa antibody
      • catenin (cadherin-associated protein) gamma (80kD) antibody
      • Catenin gamma antibody
      • CTNNG antibody
      • Desmoplakin 3 antibody
      • Desmoplakin III antibody
      • Desmoplakin-3 antibody
      • Desmoplakin3 antibody
      • DesmoplakinIII antibody
      • DP 3 antibody
      • DP III antibody
      • DP3 antibody
      • DPIII antibody
      • gamma catenin antibody
      • Junction plakoglobin antibody
      • JUP antibody
      • OTTHUMP00000164732 antibody
      • OTTHUMP00000164735 antibody
      • OTTHUMP00000164738 antibody
      • PDGB antibody
      • PKGB antibody
      • PLAK_HUMAN antibody
      • PLAKOGLOBIN antibody
      see all

    Anti-gamma Catenin antibody [M111] images



    • Predicted band size : 80 kDa

    References for Anti-gamma Catenin antibody [M111] (ab29040)

    ab29040 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Sample Human Cell lysate - whole cell (nasopharyngeal carcinoma cell line)
    Loading amount 10 µg
    Specification nasopharyngeal carcinoma cell line
    Gel Running Conditions Reduced Denaturing (8%)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C
    Username

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    Verified customer

    Submitted Jun 08 2010

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"