Anti-gamma H2A.X (phospho S139) antibody (ab11174)

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ab11174 has been referenced in 35 publications.

  • Piya S  et al. Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia. Blood 128:1260-9 (2016). PubMed: 27268264
  • Gunn AR  et al. The role of ADP-ribosylation in regulating DNA interstrand crosslink repair. J Cell Sci 129:3845-3858 (2016). PubMed: 27587838
  • Detappe A  et al. Key clinical beam parameters for nanoparticle-mediated radiation dose amplification. Sci Rep 6:34040 (2016). IHC-P ; Mouse . PubMed: 27658637
  • Gao R  et al. Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3. PLoS Genet 11:e1004834 (2015). WB ; Human . PubMed: 25590633
  • Doldi V  et al. Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation. Oncotarget 6:31441-60 (2015). ICC/IF ; Human . PubMed: 26375444
  • Chayka O  et al. Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells. J Biol Chem 290:2198-212 (2015). WB ; Human . PubMed: 25477524
  • Vasudevarao MD  et al. Naphthoquinone-mediated inhibition of lysine acetyltransferase KAT3B/p300, basis for non-toxic inhibitor synthesis. J Biol Chem 289:7702-17 (2014). WB . PubMed: 24469461
  • Sutherland JM  et al. Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression. Biol Reprod 90:92 (2014). IHC-P ; Mouse . PubMed: 24671879
  • Lu H  et al. Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis 5:e1226 (2014). WB, ICC/IF ; Human . PubMed: 24832598
  • Kalamida D  et al. Important role of autophagy in endothelial cell response to ionizing radiation. PLoS One 9:e102408 (2014). ICC/IF ; Human . PubMed: 25010689
  • Datta S  et al. Distinct distribution pattern of hepatitis B virus genotype C and D in liver tissue and serum of dual genotype infected liver cirrhosis and hepatocellular carcinoma patients. PLoS One 9:e102573 (2014). ICC/IF ; Human . PubMed: 25032957
  • Gangoda L  et al. Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice. Cell Death Differ N/A:N/A (2014). PubMed: 25012505
  • Vassileva I  et al. The mammalian INO80 chromatin remodeling complex is required for replication stress recovery. Nucleic Acids Res 42:9074-86 (2014). ICC/IF ; Human . PubMed: 25016522
  • Katsogiannou M  et al. The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. Mol Cell Proteomics 13:3585-601 (2014). WB . PubMed: 25277244
  • Ivanov A  et al. Lysosome-mediated processing of chromatin in senescence. J Cell Biol 202:129-43 (2013). PubMed: 23816621
  • Zhang X  et al. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. J Biol Chem 288:22042-56 (2013). PubMed: 23737518
  • Boohaker RJ  et al. ATM-mediated Snail Serine 100 phosphorylation regulates cellular radiosensitivity. Radiother Oncol N/A:N/A (2013). PubMed: 23891091
  • Couto CA  et al. Nonhomologous end-joining promotes resistance to DNA damage in the absence of an ADP-ribosyltransferase that signals DNA single strand breaks. J Cell Sci 126:3452-61 (2013). PubMed: 23750002
  • Zhu J  et al. Comparison of toxicity of benzene metabolite hydroquinone in hematopoietic stem cells derived from murine embryonic yolk sac and adult bone marrow. PLoS One 8:e71153 (2013). ICC/IF ; Mouse . PubMed: 23940708
  • Rosner A  et al. Germ lineage properties in the urochordate Botryllus schlosseri - From markers to temporal niches. Dev Biol 384:356-74 (2013). PubMed: 24120376
  • Mitchell JK  et al. Baculovirus F-box protein LEF-7 modifies the host DNA damage response to enhance virus multiplication. J Virol 87:12592-9 (2013). PubMed: 24027328
  • Gavvovidis I  et al. A novel MCPH1 isoform complements the defective chromosome condensation of human MCPH1-deficient cells. PLoS One 7:e40387 (2012). Human . PubMed: 22952573
  • Ring H  et al. GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium. PLoS One 7:e36874 (2012). ICC/IF ; Chicken . PubMed: 22590629
  • Zhang YW  et al. Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells. Nucleic Acids Res 39:3607-20 (2011). Flow Cyt . PubMed: 21227924
  • Hu Y  et al. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev 25:685-700 (2011). WB, ICC/IF . PubMed: 21406551
  • Colpitts TM  et al. Dengue virus capsid protein binds core histones and inhibits nucleosome formation in human liver cells. PLoS One 6:e24365 (2011). WB ; Human . PubMed: 21909430
  • Kirwan M  et al. Dyskeratosis congenita and the DNA damage response. Br J Haematol 153:634-43 (2011). Flow Cyt ; Human . PubMed: 21477209
  • Quennet V  et al. CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. Nucleic Acids Res 39:2144-52 (2011). ICC/IF ; Human . PubMed: 21087997
  • Sheu JJ  et al. Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. J Biol Chem 285:38260-9 (2010). ICC/IF ; Human . PubMed: 20923775
  • Folini M  et al. Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer. Biochem Pharmacol 79:1781-90 (2010). ICC/IF ; Human . PubMed: 20206144
  • Folini M  et al. miR-21: an oncomir on strike in prostate cancer. Mol Cancer 9:12 (2010). ICC/IF ; Human . PubMed: 20092645
  • Yoshimura K  et al. Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). Proc Natl Acad Sci U S A 106:9280-5 (2009). ICC/IF ; Mouse . PubMed: 19470456
  • Sacchetti P  et al. Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell 5:409-19 (2009). WB ; Mouse . PubMed: 19796621
  • Alton M  et al. The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary. Reproduction 135:241-52 (2008). PubMed: 18239052
  • McManus KJ & Hendzel MJ ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol Biol Cell 16:5013-25 (2005). ICC/IF . PubMed: 16030261