Anti-gamma H2A.X (phospho S139) antibody - ChIP Grade (ab2893)

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ab2893 has been referenced in 49 publications.

  • Su CH  et al. An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity. PLoS One 11:e0156378 (2016). ChIP ; Human . PubMed: 27228173
  • Thompson CM  et al. Synchrotron-based imaging of chromium and ?-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water. Toxicol Sci 143:16-25 (2015). IHC ; Mouse . PubMed: 25352572
  • Dvash E  et al. Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun 6:10112 (2015). IHC ; Mouse . PubMed: 26656251
  • Slatter TL  et al. Smoking during pregnancy causes double-strand DNA break damage to the placenta. Hum Pathol 45:17-26 (2014). IHC-P ; Human . PubMed: 24125744
  • Yang Y  et al. The interaction of the atm genotype with inflammation and oxidative stress. PLoS One 9:e85863 (2014). IHC-FoFr ; Mouse . PubMed: 24465754
  • Marongiu F  et al. Clearance of senescent hepatocytes in a neoplastic-prone microenvironment delays the emergence of hepatocellular carcinoma. Aging (Albany NY) 6:26-34 (2014). IHC-Fr ; Rat . PubMed: 24464501
  • Hagelkruys A  et al. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development 141:604-16 (2014). IHC-P ; Mouse . PubMed: 24449838
  • Suttkus A  et al. Aggrecan, link protein and tenascin-R are essential components of the perineuronal net to protect neurons against iron-induced oxidative stress. Cell Death Dis 5:e1119 (2014). IHC-Fr ; Mouse . PubMed: 24625978
  • Stimpson KM  et al. Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS One 9:e92432 (2014). IF ; Human . PubMed: 24662969
  • Shahar OD  et al. A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair. Nucleic Acids Res 42:5689-701 (2014). WB ; Human . PubMed: 24682826
  • Mikawa T  et al. Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2. J Cell Biol 204:729-45 (2014). PubMed: 24567357
  • Jansa P  et al. Dosage compensation of an aneuploid genome in mouse spermatogenic cells. Biol Reprod 90:124 (2014). Mouse . PubMed: 24790161
  • Larin M  et al. Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair. Nucleic Acids Res N/A:N/A (2014). ICC/IF ; Mouse . PubMed: 25056314
  • Hill SJ  et al. BRCA1 pathway function in basal-like breast cancer cells. Mol Cell Biol 34:3828-42 (2014). PubMed: 25092866
  • Basheva EA  et al. Chromosome synapsis and recombination in simple and complex chromosomal heterozygotes of tuco-tuco (Ctenomys talarum: Rodentia: Ctenomyidae). Chromosome Res 22:351-63 (2014). PubMed: 24924853
  • Ubil E  et al. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature 514:585-90 (2014). Histology, Immunomicroscopy, IHC, Alexa Fluor® 680 ; Mouse . PubMed: 25317562
  • Jadav RS  et al. Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair. J Biol Chem 288:3312-21 (2013). ICC/IF ; Mouse . PubMed: 23255604
  • Banh S & Hales BF Hydroxyurea exposure triggers tissue-specific activation of p38 mitogen-activated protein kinase signaling and the DNA damage response in organogenesis-stage mouse embryos. Toxicol Sci 133:298-308 (2013). IHC-P ; Mouse . PubMed: 23492809
  • Hagen KR  et al. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis. Cell Div 8:10 (2013). ICC/IF ; Human . PubMed: 23886499
  • Koundrioukoff S  et al. Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity. PLoS Genet 9:e1003643 (2013). PubMed: 23874235
  • Seo J  et al. Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation. Nucleic Acids Res N/A:N/A (2013). WB, ChIP ; Human . PubMed: 24163101
  • Sousa MM  et al. An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells. PLoS One 8:e55493 (2013). WB ; Human . PubMed: 23405159
  • Oshikawa M  et al. Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development 140:2310-20 (2013). IHC-Fr ; Mouse . PubMed: 23615279
  • Bandi S  et al. Spontaneous origin from human embryonic stem cells of liver cells displaying conjoint meso-endodermal phenotype with hepatic functions. J Cell Sci 125:1274-83 (2012). IHC-FoFr . PubMed: 22349702
  • Sustácková G  et al. Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin. J Cell Physiol 227:1838-50 (2012). ICC/IF . PubMed: 21732356
  • Haefeli RH  et al. NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels. PLoS One 6:e17963 (2011). ICC/IF ; Human . PubMed: 21483849
  • Cherubini G  et al. The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination. Nucleic Acids Res : (2011). ICC/IF ; Human . PubMed: 21421559
  • Bártová E  et al. Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells. PLoS One 6:e27281 (2011). ICC/IF ; Mouse . PubMed: 22164208
  • Hanssen-Bauer A  et al. XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage. Environ Mol Mutagen 52:623-35 (2011). PubMed: 21786338
  • Curtis CD  et al. Immunohistochemical analysis of oxidative stress and DNA repair proteins in normal mammary and breast cancer tissues. BMC Cancer 10:9 (2010). IHC-P ; Human . PubMed: 20064251
  • Mondal NK  et al. Micronucleus formation, DNA damage and repair in premenopausal women chronically exposed to high level of indoor air pollution from biomass fuel use in rural India. Mutat Res 697:47-54 (2010). ICC ; Human . PubMed: 20156583
  • Zhu H  et al. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS One 5: (2010). WB ; Human . PubMed: 20700465
  • Stimpson KM  et al. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. PLoS Genet 6: (2010). ICC/IF ; Human . PubMed: 20711355
  • Kim J  et al. Repetitive exposure to a 60-Hz time-varying magnetic field induces DNA double-strand breaks and apoptosis in human cells. Biochem Biophys Res Commun 400:739-44 (2010). WB ; Human . PubMed: 20816755
  • Rantala JK  et al. Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2. Neoplasia 12:877-88 (2010). PubMed: 21082043
  • Tuduri S  et al. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat Cell Biol : (2009). ChIP/Chip ; Human . PubMed: 19838172
  • Chen S  et al. Transcriptional Co-activator p300 Regulates Glucose Induced Gene Expression in the Endothelial Cells. Am J Physiol Endocrinol Metab : (2009). ICC/IF ; Human . PubMed: 19903865
  • Caslini C  et al. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol 29:4519-26 (2009). PubMed: 19528237
  • Sciurano RB  et al. Focal spermatogenesis originates in euploid germ cells in classical Klinefelter patients. Hum Reprod 24:2353-60 (2009). PubMed: 19443454
  • Heo K  et al. FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16. Mol Cell 30:86-97 (2008). WB ; Human . PubMed: 18406329
  • Leduc F  et al. DNA damage response during chromatin remodeling in elongating spermatids of mice. Biol Reprod 78:324-32 (2008). PubMed: 18032420
  • Gu BW  et al. A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice. Proc Natl Acad Sci U S A 105:10173-8 (2008). WB, ICC/IF ; Mouse . PubMed: 18626023
  • Huang FC  et al. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells. Mol Cancer Res 6:955-64 (2008). PubMed: 18515756
  • Dungey FA  et al. Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential. Int J Radiat Oncol Biol Phys 72:1188-97 (2008). ICC/IF ; Human . PubMed: 18954712
  • Sciurano R  et al. The asynaptic chromatin in spermatocytes of translocation carriers contains the histone variant gamma-H2AX and associates with the XY body. Hum Reprod 22:142-50 (2007). PubMed: 16920723
  • Albert JM  et al. Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models. Clin Cancer Res 13:3033-42 (2007). PubMed: 17505006
  • Morency E  et al. A novel cell response triggered by interphase centromere structural instability. J Cell Biol 177:757-68 (2007). ICC/IF ; Human . PubMed: 17548509
  • Chan KL  et al. BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J 26:3397-409 (2007). PubMed: 17599064
  • McManus KJ & Hendzel MJ ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol Biol Cell 16:5013-25 (2005). ICC/IF . PubMed: 16030261

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