Anti-gamma H2A.X (phospho S140) antibody [3F2] (ab22551)

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ab22551 has been referenced in 33 publications.

  • Schipler A  et al. Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment. Nucleic Acids Res 44:7673-90 (2016). ICC/IF . PubMed: 27257076
  • Pellarin I  et al. The Architectural Chromatin Factor High Mobility Group A1 Enhances DNA Ligase IV Activity Influencing DNA Repair. PLoS One 11:e0164258 (2016). WB, ICC/IF . PubMed: 27723831
  • Matveevsky S  et al. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation? Sci Rep 6:29949 (2016). ICC/IF . PubMed: 27425629
  • Polettini J  et al. Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition? PLoS One 10:e0137188 (2015). ICC/IF ; Human . PubMed: 26397719
  • Suchánková J  et al. PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage. Eur J Histochem 58:2389 (2014). ICC/IF . PubMed: 24998928
  • Makino Y  et al. Generation of a dual-color reporter mouse line to monitor spermatogenesis in vivo. Front Cell Dev Biol 2:30 (2014). Mouse . PubMed: 25364737
  • Slatter TL  et al. Smoking during pregnancy causes double-strand DNA break damage to the placenta. Hum Pathol 45:17-26 (2014). IHC-P ; Human . PubMed: 24125744
  • Guo P  et al. MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated. Exp Cell Res 320:200-8 (2014). WB . PubMed: 24211747
  • Huttner HB  et al. The age and genomic integrity of neurons after cortical stroke in humans. Nat Neurosci 17:801-3 (2014). Human . PubMed: 24747576
  • Wang M  et al. EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation. Cancer Res 74:2825-34 (2014). ICC/IF ; Human . PubMed: 24648348
  • Wichmann C  et al. Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors. Leukemia N/A:N/A (2014). PubMed: 24897507
  • Grassilli E  et al. GSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosis. PLoS One 9:e100947 (2014). ICC/IF ; Human . PubMed: 24984063
  • Chapmana AM  et al. IL-13 overexpression in mouse lungs triggers systemic genotoxicity in peripheral blood. Mutat Res 769:100-7 (2014). PubMed: 25400503
  • Al-Ubaidi FL  et al. Castration therapy results in decreased Ku70 levels in prostate cancer. Clin Cancer Res 19:1547-56 (2013). Human . PubMed: 23349316
  • Dai C  et al. Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors. PLoS One 8:e63054 (2013). ICC/IF ; Human . PubMed: 23675453
  • Huang SY  et al. TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs. Nucleic Acids Res 41:7793-803 (2013). PubMed: 23775789
  • Gaber N  et al. Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation. Am J Pathol 183:720-34 (2013). Flow Cyt . PubMed: 23871585
  • Pfäffle HN  et al. EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity. Cancer Res 73:6254-63 (2013). Human . PubMed: 23966292
  • Li J  et al. Synergistic combination of valproic acid and oncolytic parvovirus H-1PV as a potential therapy against cervical and pancreatic carcinomas. EMBO Mol Med 5:1537-55 (2013). WB ; Human . PubMed: 24092664
  • Viñas-Castells R  et al. Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability. Nucleic Acids Res N/A:N/A (2013). WB . PubMed: 24157836
  • Lee YY  et al. BCLAF1 is a radiation-induced H2AX-interacting partner involved in ?H2AX-mediated regulation of apoptosis and DNA repair. Cell Death Dis 3:e359 (2012). WB ; Human . PubMed: 22833098
  • Mao Z  et al. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proc Natl Acad Sci U S A 109:11800-5 (2012). ICC/IF ; Human . PubMed: 22753495
  • Lukas C  et al. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat Cell Biol 13:243-53 (2011). ICC/IF ; Human . PubMed: 21317883
  • Kosar M  et al. Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a). Cell Cycle 10:457-68 (2011). PubMed: 21248468
  • Yin DT  et al. Germline Stem Cell Gene PIWIL2 Mediates DNA Repair through Relaxation of Chromatin. PLoS One 6:e27154 (2011). ICC/IF ; Mouse . PubMed: 22110608
  • Petermann E  et al. Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair. Mol Cell 37:492-502 (2010). WB ; Human . PubMed: 20188668
  • Wu M  et al. Selenium compounds activate early barriers of tumorigenesis. J Biol Chem 285:12055-62 (2010). ICC/IF ; Human . PubMed: 20157118
  • Roig AI  et al. Two- and three-dimensional models for risk assessment of radiation-enhanced colorectal tumorigenesis. Radiat Res 171:33-40 (2009). ICC/IF ; Human . PubMed: 19138051
  • Song R  et al. Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nat Genet 41:488-93 (2009). IHC-P ; Mouse . PubMed: 19305411
  • Sak A  et al. Long-term in vivo effects of cisplatin on gamma-H2AX foci signaling in peripheral lymphocytes of tumor patients after irradiation. Clin Cancer Res 15:2927-34 (2009). ICC/IF ; Human . PubMed: 19336520
  • Brower JV  et al. Adenine nucleotide translocase 4 deficiency leads to early meiotic arrest of murine male germ cells. Reproduction 138:463-70 (2009). PubMed: 19556438
  • Sasaki T  et al. Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis. J Cell Biol 182:449-58 (2008). ICC/IF ; Mouse . PubMed: 18678708
  • Okada Y  et al. Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. Nature 450:119-23 (2007). IHC-P ; Mouse . PubMed: 17943087