Overview

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab46201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa corresponding to the molecular weight of the full length Gamma Synuclein recombinant protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
    • Tissue specificityHighly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
    • Sequence similaritiesBelongs to the synuclein family.
    • Post-translational
      modifications
      Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
    • Cellular localizationCytoplasm > perinuclear region. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
    • Information by UniProt
    • Database links
    • Alternative names
      • BCSG1 antibody
      • Breast cancer specific gene 1 protein antibody
      • Breast cancer specific protein 1 antibody
      • Breast cancer-specific gene 1 protein antibody
      • Gamma synuclein antibody
      • Gamma-synuclein antibody
      • Persyn antibody
      • PRSN antibody
      • SNCG antibody
      • SR antibody
      • Synoretin antibody
      • Synuclein gamma antibody
      • synuclein, gamma (breast cancer-specific protein 1) antibody
      • SYUG_HUMAN antibody
      see all

    Anti-gamma Synuclein antibody images

    • Anti-gamma Synuclein antibody (ab46201) at 0.5 µg/ml + Recombinant Human gamma Synuclein protein (ab48712) at 0.05 µg

      Secondary
      Goat polyclonal to rabbit IgG - H&L - Pre adsorbed (HRP) at 1/3000 dilution

      Performed under reducing conditions.

      Observed band size : 15 kDa (why is the actual band size different from the predicted?)

    References for Anti-gamma Synuclein antibody (ab46201)

    ab46201 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"