Anti-Ganglioside GD2 antibody [11H3] (ab82717)

Overview

  • Product nameAnti-Ganglioside GD2 antibody [11H3]
    See all Ganglioside GD2 primary antibodies
  • Description
    Mouse monoclonal [11H3] to Ganglioside GD2
  • Specificityab82717 reacts specifically with Ganglioside GD2. It does not cross reacts with others gangliosides.
  • Tested applicationsSuitable for: Thin Layer Chromatography, WB, ELISAmore details
  • Immunogen

    Ganglioside GD2

Properties

Applications

Our Abpromise guarantee covers the use of ab82717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Thin Layer Chromatography
WB
ELISA
  • Application notesELISA: 1/10 - 1/100.
    TLC: Use at an assay dependent dilution.
    WB: 1/5 - 1/50.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceGangliosides are a group of galactose-containing cerebrosides found in the surface membranes of nerve cells. Ganglioside GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans. GD2 is a suitable target for immunotherapy with monoclonal antibodies or with artificial T cell receptors due to its relatively tumor specific expression.
    • Alternative names
      • Disialoganglioside GD2 antibody

    References for Anti-Ganglioside GD2 antibody [11H3] (ab82717)

    ab82717 has not yet been referenced specifically in any publications.

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