Anti-Ganglioside GD3 antibody [4F6] (ab6217)

Overview

  • Product nameAnti-Ganglioside GD3 antibody [4F6]
    See all Ganglioside GD3 primary antibodies
  • Description
    Mouse monoclonal [4F6] to Ganglioside GD3
  • SpecificityThe antibody reacts specifically with GD3 ganglioside (NeuAcá2-8NeuAcá2-3Galâ1-4Glcâ1-1Cer) and cross reacts with 9-O-AcGD3 ganglioside (9OAcNeuAcá2-8NeuAcá2-3Galâ1-4Glcâ1-1Cer) and GT1a ganglioside ganglioside (NeuAcá2-8NeuAcá2-3Galâ1-4GalNAcâ1-4(NeuAcá2-3)Galâ1-4Glcâ1-1Cer)
  • Tested applicationsSuitable for: WB, ELISA, Thin Layer Chromatographymore details

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: Tissue Culture Supernatant
  • PurityTissue culture supernatant
  • ClonalityMonoclonal
  • Clone number4F6
  • Myelomaunknown
  • IsotypeIgG3
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab6217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
Thin Layer Chromatography
  • Application notesELISA: 1/10 - 1/100.
    TLC: Use at an assay dependant dilution.
    WB: 1/10 - 1/100.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceAlmost all melanomas, astrocytomas, a proportion of sarcomas, a small number of carcinomas, some nevi, as well as normal melanocytes express GD3 antigen. It is one of the most important markers for malignant melanoma. Antibodies to the GD3 ganglioside can induce partial remission of tumor growth in animals as well as in Humans via enhancement of cytotoxic and proliferative response of lymphocytes.
    • Alternative names
      • GD3 antibody

    References for Anti-Ganglioside GD3 antibody [4F6] (ab6217)

    ab6217 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. This antibody has not yet been tested for IHC. Should you decide to go ahead and test this antibody, please let us know how you get on, and in return we will forward a USD15/EUR15/GBP10 Amazon gift voucher.

    The subtype is IgG3 - I'll add this information to the datasheet.

    All the information we have for this monoclonal antibody is on the datasheet. It is supplied as a tissue culture supernatant, the concentration has not been determined, but there are suggested dilutions for ELISA and WB on the datasheet. You may also l...

    Read More

    This antibody has not been tested in immunohistochemistry, and so we cannot guarantee that the antibody will work. All the data that we have for this antibody is on the datasheet.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"