Overview

  • Product nameAnti-GAP43 antibody
    See all GAP43 primary antibodies
  • Description
    Mouse monoclonal to GAP43
  • Specificityab117265 reacts with both phosphorylated and unphosphorylated forms of the GAP43 protein.
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Rabbit, Chicken, Human, Snake
  • Immunogen

    Full length native Rat GAP43 (both phosphorylated & unphosphorylated forms).

  • Positive control
    • Human Brain (Putamen, Neuropil) tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab117265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa.
ELISA Use a concentration of 0.1 - 1 µg/ml.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IHC-Fr Use a concentration of 5 µg/ml.

Target

  • FunctionThis protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.
  • Sequence similaritiesBelongs to the neuromodulin family.
    Contains 1 IQ domain.
  • Post-translational
    modifications
    Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
  • Cellular localizationCell membrane. Cell projection > growth cone membrane. Cell junction > synapse. Cytoplasmic surface of growth cone and synaptic plasma membranes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Axonal membrane protein GAP 43 antibody
    • Axonal membrane protein GAP-43 antibody
    • B 50 antibody
    • Calmodulin binding protein P 57 antibody
    • F1 antibody
    • GAP 43 antibody
    • GAP43 antibody
    • Growth Associated Protein 43 antibody
    • Growth-associated protein 43 antibody
    • Nerve Growth Related Peptide antibody
    • Nerve growth related peptide GAP43 antibody
    • NEUM_HUMAN antibody
    • Neural phosphoprotein B 50 antibody
    • Neural phosphoprotein B-50 antibody
    • Neuromodulin antibody
    • Neuron growth associated protein 43 antibody
    • PP46 antibody
    • Protein F1 antibody
    • QtrA-11580 antibody
    • QtrA-13071 antibody
    see all

Anti-GAP43 antibody images

  • ab117265, at 5 µg/ml, staining GAP43 in Formalin-fixed, Paraffin-embedded Human Brain, Putamen, Neuropil tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-GAP43 antibody (ab117265)

ab117265 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"