• Product nameAnti-GAPDHS antibody [Hs-8]
    See all GAPDHS primary antibodies
  • Description
    Mouse monoclonal [Hs-8] to GAPDHS
  • SpecificityThe antibody Hs-8 reacts with GAPDHS, the sperm-specific glyceraldehyde phosphate dehydrogenase, previously identified under the general name "intra-acrosomal protein".
  • Tested applicationsSuitable for: ICC, WBmore details
  • Species reactivity
    Reacts with: Human, Pig
  • Immunogen

    Tissue, cells or virus corresponding to GAPDHS. Freshly ejaculated human sperm were washed in PBS & extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid & then used for immunization.



Our Abpromise guarantee covers the use of ab4569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 10 µg/ml.
WB Use at an assay dependent concentration. Predicted molecular weight: 45 kDa.


  • FunctionMay play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility.
  • Tissue specificityTestis specific.
  • PathwayCarbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.
  • Sequence similaritiesBelongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  • DomainThe testis-specific N-terminal extension mediates tight association with the cytoskeletal fibrous sheath of the spermatozoa flagellum, possibly via interchain disulfide-bonding of Cys-21 with sheath components.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • G3PT_HUMAN antibody
    • GAPD2 antibody
    • GAPDH 2 antibody
    • GAPDH-2 antibody
    • GAPDH2 antibody
    • GAPDHS antibody
    • GAPDS antibody
    • Glyceraldehyde 3 phosphate dehydrogenase spermatogenic antibody
    • Glyceraldehyde 3 phosphate dehydrogenase, testis specific antibody
    • Glyceraldehyde-3-phosphate dehydrogenase antibody
    • HSD 35 antibody
    • HSD35 antibody
    • Spermatogenic cell specific glyceraldehyde 3 phosphate dehydrogenase 2 antibody
    • Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2 antibody
    • Spermatogenic glyceraldehyde 3 phosphate dehydrogenase antibody
    • Spermatogenic glyceraldehyde-3-phosphate dehydrogenase antibody
    • testis-specific antibody
    see all

References for Anti-GAPDHS antibody [Hs-8] (ab4569)

This product has been referenced in:
  • Chládek D  et al. [Use of human sperm protein monoclonal antibodies in the diagnosis of sperm pathology and selection of a suitable assisted reproduction method for fertilization] Ceska Gynekol 65:28-32 (2000). Read more (PubMed: 10750294) »
  • Tepla O. In vitro Fertilization & Human Reproduc. Genetics. :107 (1999). Read more (PubMed: ) »

See all 2 Publications for this product

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Currently, we have 2 vials in our UK stock (both from batch: 1301990). The unit size is

100.0 µg and the concentration is 1 mg/ml.

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