Anti-GAS41 antibody - N-terminal (ab71260)

Overview

  • Product nameAnti-GAS41 antibody - N-terminal
    See all GAS41 primary antibodies
  • Description
    Rabbit polyclonal to GAS41 - N-terminal
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the N-terminal region of human GAS41 conjugated to KLH

  • Positive control
    • HepG2 cell line lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab71260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 30 kDa (predicted molecular weight: 27 kDa).

Target

  • FunctionComponent of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
  • Tissue specificityExpressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • Sequence similaritiesContains 1 YEATS domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4930573H17Rik antibody
    • B230215M10Rik antibody
    • GAS 41 antibody
    • Gas41 antibody
    • glioma amplified sequence 41 antibody
    • Glioma-amplified sequence 41 antibody
    • glioma-amplified sequence-41 antibody
    • gliomaamplified sequence 41 antibody
    • gliomaamplified sequence41 antibody
    • NUBI 1 antibody
    • NuBI-1 antibody
    • NuBI1 antibody
    • NuMA binding protein 1 antibody
    • NuMA-binding protein 1 antibody
    • YAF9 antibody
    • YEATS domain containing 4 antibody
    • YEATS domain containing4 antibody
    • YEATS domain-containing protein 4 antibody
    • YEATS4 antibody
    • YETS4_HUMAN antibody
    see all

Anti-GAS41 antibody - N-terminal images

  • Anti-GAS41 antibody - N-terminal (ab71260) at 1/100 dilution + HepG2 cell line lysate at 12.5 µg

    Predicted band size : 27 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

References for Anti-GAS41 antibody - N-terminal (ab71260)

ab71260 has not yet been referenced specifically in any publications.

Product Wall

I am very pleased to hear you would like to accept our offer and test ab71260 in mouse. This code will give you: 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for mouse and include this code in the ...

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Thank you very much for your interest in ab71260.

To our knowledge, ab71260 has not been tested in mouse, however the immunogen sequence shares 100% identity with the mouse sequence. Therefore, I can offer a discount off a future purchase if y...

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Thank you for contacting Abcam.


Unfortunately, we do not know the identity of the higher molecular weight band in the WB image for ab71260.


I am currently checking with the lab on the immunogen sequence to see how similar it...

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Application Western blot
Sample Human Cell lysate - whole cell (cervix uteri (hela cells))
Loading amount 50 µg
Specification cervix uteri (hela cells)
Gel Running Conditions Reduced Denaturing (12%)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Dr. Angelique Whitehurst

Verified customer

Submitted Sep 07 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"