• Product name
  • Description
    Rabbit polyclonal to Gastrin
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Dog
  • Immunogen

    Synthetic peptide:


    conjugated to BSA, corresponding to N terminal amino acids 1-13 of Human Gastrin.

  • Positive control
    • Pituitary or stomach
  • General notes

    This antibody may be used to study the differential tissue expression and intracellular and subcellular localization of gastrin in neuroendocrine cells of the gastrointestinal tract,and in the CNS. Antibodies to gastrin are also useful for the identificationand detection of gastrin in normal and neoplastic tissue.



Our Abpromise guarantee covers the use of ab16035 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200.


  • Function
    Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
  • Sequence similarities
    Belongs to the gastrin/cholecystokinin family.
  • Post-translational
    Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
    Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Component II antibody
    • G14 antibody
    • G17 antibody
    • G34 antibody
    • G52 antibody
    • G6 antibody
    • GAS antibody
    • Gast antibody
    • GAST_HUMAN antibody
    • Gastrin antibody
    • Gastrin component I antibody
    • Gastrin component II antibody
    • Gastrin component III antibody
    • Gastrin precursor antibody
    • Gastrin-14 antibody
    • Gastrin-17 antibody
    • Gastrin-34 antibody
    • Gastrin-52 antibody
    • Gastrin-6 antibody
    • Gastrin-71 antibody
    see all

Anti-Gastrin antibody images

  • ab16035 staining human Gastrin at 1/200 dilution in stomach by Immunohistochemistry (FFPE-sections).

References for Anti-Gastrin antibody (ab16035)

This product has been referenced in:
  • Lennerz JK  et al. The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma. Am J Pathol 177:1514-33 (2010). IHC-P ; Human . Read more (PubMed: 20709804) »

See 1 Publication for this product

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We do not have any experimental data regarding the cross-reactivity of ab16035 with CCK. I compared the immunogen sequence for ab16035 with that of the CCK sequence (P06307-Uniprot) and the percentage homology is ...

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Thank you for contacting us.

We have not experimentally tested the possibility of ab16035 cross reactivity with CCK. So I am sorry we cannot confirm it 100%. The recommendations we gave were based on the minimal sequence homology between CCK...

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