Overview

  • Product name
    Anti-GATA2 (phospho S401) antibody
    See all GATA2 primary antibodies
  • Description
    Rabbit polyclonal to GATA2 (phospho S401)
  • Host species
    Rabbit
  • Specificity
    ab138451 detects endogenous levels of GATA2 only when phosphorylated at S401.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic phospho-peptide against the C-terminal region, surrounding S401 of the Human GATA2 protein.

  • Positive control
    • WB: Extracts from COS7 cells treated with 20ng/ml of TNF for 5 minutes.

Properties

Applications

Our Abpromise guarantee covers the use of ab138451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 50 kDa.

Target

  • Function
    Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.
  • Tissue specificity
    Endothelial cells.
  • Sequence similarities
    Contains 2 GATA-type zinc fingers.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • DCML antibody
    • Endothelial transcription factor GATA 2 antibody
    • Endothelial transcription factor GATA-2 antibody
    • Endothelial transcription factor GATA2 antibody
    • FLJ45948 antibody
    • GATA 2 antibody
    • GATA binding protein 2 antibody
    • GATA-binding protein 2 antibody
    • Gata2 antibody
    • GATA2_HUMAN antibody
    • IMD21 antibody
    • MGC2306 antibody
    • MONOMAC antibody
    • NFE 1B antibody
    • NFE1B antibody
    • OTTHUMP00000216240 antibody
    see all

Images

  • Anti-GATA2 (phospho S401) antibody (ab138451) at 1/500 dilution + Extracts from COS7 cells treated with 20 ng/ml of TNF for 5 minutes.

    Predicted band size: 50 kDa

References

This product has been referenced in:
  • Bhattacharyya S  et al. Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1. J Biol Chem 290:10764-74 (2015). WB . Read more (PubMed: 25784556) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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