Anti-GATA3 antibody [KT77] (ab110093)
Key features and details
- Rat monoclonal [KT77] to GATA3
- Suitable for: WB, ICC/IF
- Reacts with: Mouse
- Isotype: IgG2a
Overview
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Product name
Anti-GATA3 antibody [KT77]
See all GATA3 primary antibodies -
Description
Rat monoclonal [KT77] to GATA3 -
Host species
Rat -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Full length protein (Mouse)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
KT77 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab110093 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/10000. Predicted molecular weight: 47 kDa.
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ICC/IF |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/10000. Predicted molecular weight: 47 kDa. |
ICC/IF
1/100 - 1/1000. |
Target
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Function
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. -
Tissue specificity
T-cells and endothelial cells. -
Involvement in disease
Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome. -
Sequence similarities
Contains 2 GATA-type zinc fingers. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 14462 Mouse
- SwissProt: P23772 Mouse
- Unigene: 313866 Mouse
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Form
There are 2 isoforms produced by alternative splicing. -
Alternative names
- GATA 3 antibody
- GATA binding factor 3 antibody
- GATA binding protein 3 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab110093 has been referenced in 2 publications.
- Bi CS et al. Calcitriol inhibits osteoclastogenesis in an inflammatory environment by changing the proportion and function of T helper cell subsets (Th2/Th17). Cell Prolif 53:e12827 (2020). PubMed: 32406154
- Newland SA et al. Type-2 innate lymphoid cells control the development of atherosclerosis in mice. Nat Commun 8:15781 (2017). IHC-Fr ; Mouse . PubMed: 28589929