Overview

  • Product nameAnti-GBA3 antibody
    See all GBA3 primary antibodies
  • Description
    Rabbit polyclonal to GBA3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide, corresponding to a region within N terminal amino acids 71-120 (LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH) of Human GBA3 (NP_066024.1).

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab118947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionGlycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
  • Tissue specificityPresent in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
  • Sequence similaritiesBelongs to the glycosyl hydrolase 1 family. Klotho subfamily.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localizationCytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • CBG antibody
    • CBGL1 antibody
    • Cytosolic beta glucosidase antibody
    • Cytosolic beta glucosidase like protein 1 antibody
    • Cytosolic beta-glucosidase antibody
    • Cytosolic beta-glucosidase-like protein 1 antibody
    • GBA3 antibody
    • GBA3_HUMAN antibody
    • GLUC antibody
    • Glucosidase beta acid 3 antibody
    • Klotho related protein antibody
    • KLRP antibody
    see all

Anti-GBA3 antibody images

  • Anti-GBA3 antibody (ab118947) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 54 kDa

References for Anti-GBA3 antibody (ab118947)

ab118947 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"