Overview

  • Product name
    Anti-GC1q R antibody [60.11] (FITC)
    See all GC1q R primary antibodies
  • Description
    Mouse monoclonal [60.11] to GC1q R (FITC)
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Tested applications
    Suitable for: WB, IP, Functional Studies, Flow Cyt, ELISAmore details
  • Species reactivity
    Reacts with: Rat, Human, Syrian hamster
  • Immunogen

    Recombinant full length mature protein, corresponding to amino acids 74-282 of Human GC1q R.

  • Epitope
    ab125138 is directed against epitopes situated within the NH2-terminal stretch of GC1q R.

Properties

Applications

Our Abpromise guarantee covers the use of ab125138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50. Predicted molecular weight: 31 kDa.
IP Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ELISA Use at an assay dependent concentration.

Target

  • Function
    Binds to the globular "heads" of C1Q thus inhibiting C1 activation.
  • Sequence similarities
    Belongs to the MAM33 family.
  • Cellular localization
    Mitochondrion matrix. Nucleus. Might also be nuclear in some cell types.
  • Information by UniProt
  • Database links
  • Alternative names
    • ASF/SF2 associated protein p32 antibody
    • C1q globular domain binding protein antibody
    • C1qBP antibody
    • C1QBP_HUMAN antibody
    • Complement component 1 q subcomponent binding protein antibody
    • Complement component 1 Q subcomponent binding protein mitochondrial antibody
    • Complement component 1 Q subcomponent-binding protein, mitochondrial antibody
    • GC1Q R antibody
    • GC1q R protein antibody
    • GC1q-R protein antibody
    • GC1QBP antibody
    • GC1QR antibody
    • globular domain of, C1q, receptor for antibody
    • Glycoprotein gC1qBP antibody
    • HABP 1 antibody
    • HABP1 antibody
    • Hyaluronan binding protein 1 antibody
    • Hyaluronan-binding protein 1 antibody
    • Mitochondrial matrix protein p32 antibody
    • p32 antibody
    • p32 splicing factor antibody
    • p33 antibody
    • Pre mrna splicing factor SF2 P32 subunit precursor antibody
    • SF2p32 antibody
    • Splicing factor SF2 associated protein antibody
    see all

References

This product has been referenced in:
  • Peerschke EI  et al. gC1qR/p33 blockade reduces Staphylococcus aureus colonization of target tissues in an animal model of infective endocarditis. Infect Immun 74:4418-23 (2006). Read more (PubMed: 16861627) »
  • Ghebrehiwet B  et al. gC1q-R/p33, a member of a new class of multifunctional and multicompartmental cellular proteins, is involved in inflammation and infection. Immunol Rev 180:65-77 (2001). Read more (PubMed: 11414365) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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