Overview

  • Product name
  • Description
    Rabbit polyclonal to GCAP2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 34-83 (SGTLFMHEFK RFFKVTDDEE ASQYVEGMFR AFDKNGDNTI DFLEYVAALN) of Human GCAP2 (NP_002089).

  • Positive control
    • U937 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab111350 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
  • Tissue specificity
    Retina. Cones and rod.
  • Sequence similarities
    Contains 4 EF-hand domains.
  • Cellular localization
    Cell membrane. Membranes of outer segment.
  • Information by UniProt
  • Database links
  • Alternative names
    • GCAP 2 antibody
    • Guanylate Cyclase Activating Protein Photoreceptor 2 antibody
    • Guanylate cyclase activator 1B antibody
    • Guanylin 2 antibody
    • Guanylyl cyclase-activating protein 2 antibody
    • GUC1B_HUMAN antibody
    • GUCA 2 antibody
    • Guca1b antibody
    see all

Images

  • Anti-GCAP2 antibody (ab111350) at 1 µg/ml + U937 cell lysate at 10 µg

    Predicted band size : 23 kDa

References

ab111350 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab111350.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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