Recombinant Anti-GCAP2 antibody [EPR14571] (ab184958)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR14571] to GCAP2
- Suitable for: WB
- Reacts with: Mouse, Rat
Related conjugates and formulations
Overview
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Product name
Anti-GCAP2 antibody [EPR14571]
See all GCAP2 primary antibodies -
Description
Rabbit monoclonal [EPR14571] to GCAP2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat
Predicted to work with: Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Mouse and rat eyeball lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR14571 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab184958 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/2000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
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Notes |
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WB
1/1000 - 1/2000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa). |
Target
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Function
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure. -
Tissue specificity
Retina. Cones and rod. -
Sequence similarities
Contains 4 EF-hand domains. -
Cellular localization
Cell membrane. Membranes of outer segment. - Information by UniProt
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Database links
- Entrez Gene: 2979 Human
- Entrez Gene: 107477 Mouse
- Entrez Gene: 316218 Rat
- Omim: 602275 Human
- SwissProt: Q9UMX6 Human
- SwissProt: Q8VBV8 Mouse
- Unigene: 446529 Human
- Unigene: 59151 Mouse
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Alternative names
- GCAP 2 antibody
- Guanylate Cyclase Activating Protein Photoreceptor 2 antibody
- Guanylate cyclase activator 1B antibody
see all
Images
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Anti-GCAP2 antibody [EPR14571] (ab184958) at 1/2000 dilution + Rat eyeball lysate at 20 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 23 kDa -
Anti-GCAP2 antibody [EPR14571] (ab184958) at 1/1000 dilution + Mouse eyeball lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 23 kDa
Datasheets and documents
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SDS download
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Datasheet download
Certificate of Compliance
References (0)
ab184958 has not yet been referenced specifically in any publications.