Overview

  • Product nameAnti-GCC2 antibody
    See all GCC2 primary antibodies
  • Description
    Rabbit polyclonal to GCC2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region between C terminal amino acids 1548-1617 of Human GCC2 (NP_852118.1)

  • Positive control
    • Mouse stomach tissue lysate; Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab107755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 196 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionGolgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 GRIP domain.
  • DomainExtended rod-like protein with coiled-coil domains.
  • Cellular localizationCytoplasm. Golgi apparatus > trans-Golgi network membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 185 kDa Golgi coiled-coil protein antibody
    • CLL-associated antigen KW-11 antibody
    • CTCL tumor antigen se1-1 antibody
    • GCC protein, 185 kD antibody
    • GCC185 antibody
    • GCC2 antibody
    • GCC2_HUMAN antibody
    • Golgi coiled coil protein GCC185 antibody
    • GRIP and coiled coil domain containing 2 antibody
    • GRIP and coiled-coil domain-containing protein 2 antibody
    • KIAA0336 antibody
    • OTTHUMP00000217161 antibody
    • Ran-binding protein 2-like 4 antibody
    • RanBP2L4 antibody
    • REN53 antibody
    • Renal carcinoma antigen NY-REN-53 antibody
    see all

Anti-GCC2 antibody images

  • Anti-GCC2 antibody (ab107755) at 1/100 dilution + Mouse stomach tissue lysate at 15 µg

    Predicted band size : 196 kDa
  • Immunohistochemistry analysis using ab107755 at 1/50 in formalin fixed and paraffin embedded Human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

References for Anti-GCC2 antibody (ab107755)

ab107755 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"