• Product nameAnti-GCET2 antibody
    See all GCET2 primary antibodies
  • Description
    Mouse polyclonal to GCET2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    GCET2 (NP_689998.1, 1-178 a.a) full-length human protein


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab69289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 21 kDa.


  • FunctionInvolved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
  • Tissue specificityExpressed in diffuse large B-cell lymphoma (DLBCL) and several germinal center (GC)-like lymphoma cell lines (at protein level). Highly expressed in normal GC lymphocytes and GC-derived malignancies. Expressed in thymus and spleen.
  • Post-translational
    Phosphorylation on tyrosine residues can be induced by IL6. Phosphorylation is mediated by LYN.
  • Cellular localizationCytoplasm. Cell membrane. It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6.
  • Information by UniProt
  • Database links
  • Alternative names
    • GCAT2 antibody
    • Gcet antibody
    • GCET2 germinal center expressed transcript 2 antibody
    • GCET2 germinal centre expressed transcript 2 antibody
    • Gcsam antibody
    • GCSAM_HUMAN antibody
    • Germinal center associated lymphoma antibody
    • Germinal center associated lymphoma protein antibody
    • Germinal center B cell associated protein 2 antibody
    • Germinal center B-cell-expressed transcript 2 protein antibody
    • Germinal center expressed transcript 2 antibody
    • Germinal center-associated lymphoma protein antibody
    • Germinal center-associated signaling and motility protein antibody
    • Germinal centre associated lymphoma antibody
    • Germinal centre associated lymphoma protein antibody
    • Germinal centre B cell associated protein 2 antibody
    • Germinal centre expressed transcript 2 antibody
    • hGAL antibody
    • M17 antibody
    • M17 L antibody
    see all

Anti-GCET2 antibody images

  • All lanes : Anti-GCET2 antibody (ab69289) at 1/1000 dilution

    Lane 1 : GCET2 transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 21 kDa

References for Anti-GCET2 antibody (ab69289)

ab69289 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Reactive tonsils, follicular lymphomas)
Specification Reactive tonsils, follicular lymphomas
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: pH 6.0
Permeabilization No
Blocking step Serum as blocking agent for 20 minute(s) · Concentration: 0% · Temperature: 37°C

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Submitted Sep 15 2010