• Product nameAnti-GCET2 antibody
    See all GCET2 primary antibodies
  • Description
    Rabbit polyclonal to GCET2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 129-178 (SLLHMPSTDP RHARSPEDEY ELLMPHRISS HFLQQPRPLM APSETQFSHL) of human GCET2 (NP_689998).

  • Positive control
    • Transfected 293T cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab86504 is purified by a peptide affinity chromatography method.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab86504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionInvolved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
  • Tissue specificityExpressed in diffuse large B-cell lymphoma (DLBCL) and several germinal center (GC)-like lymphoma cell lines (at protein level). Highly expressed in normal GC lymphocytes and GC-derived malignancies. Expressed in thymus and spleen.
  • Post-translational
    Phosphorylation on tyrosine residues can be induced by IL6. Phosphorylation is mediated by LYN.
  • Cellular localizationCytoplasm. Cell membrane. It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6.
  • Information by UniProt
  • Database links
  • Alternative names
    • GCAT2 antibody
    • Gcet antibody
    • GCET2 germinal center expressed transcript 2 antibody
    • GCET2 germinal centre expressed transcript 2 antibody
    • Gcsam antibody
    • GCSAM_HUMAN antibody
    • Germinal center associated lymphoma antibody
    • Germinal center associated lymphoma protein antibody
    • Germinal center B cell associated protein 2 antibody
    • Germinal center B-cell-expressed transcript 2 protein antibody
    • Germinal center expressed transcript 2 antibody
    • Germinal center-associated lymphoma protein antibody
    • Germinal center-associated signaling and motility protein antibody
    • Germinal centre associated lymphoma antibody
    • Germinal centre associated lymphoma protein antibody
    • Germinal centre B cell associated protein 2 antibody
    • Germinal centre expressed transcript 2 antibody
    • hGAL antibody
    • M17 antibody
    • M17 L antibody
    see all

Anti-GCET2 antibody images

  • Anti-GCET2 antibody (ab86504) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 21 kDa
    Observed band size : 21 kDa
    Additional bands at : 62 kDa. We are unsure as to the identity of these extra bands.

References for Anti-GCET2 antibody (ab86504)

ab86504 has not yet been referenced specifically in any publications.

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