Overview

  • Product nameAnti-GCHFR antibody
    See all GCHFR primary antibodies
  • Description
    Rabbit polyclonal to GCHFR
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from an internal sequence of Human GCHFR.

  • Positive control
    • Human colon carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab110161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
  • Tissue specificityIn epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
  • Sequence similaritiesBelongs to the GFRP family.
  • Cellular localizationNucleus. Nucleus membrane. Cytoplasm > cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • GCHFR antibody
    • GFRP antibody
    • GFRP_HUMAN antibody
    • GTP cyclohydrolase 1 feedback regulatory protein antibody
    • GTP cyclohydrolase I feedback regulator antibody
    • GTP cyclohydrolase I feedback regulatory protein antibody
    • HsT16933 antibody
    • MGC138467 antibody
    • MGC138469 antibody
    • p35 antibody
    see all

Anti-GCHFR antibody images

  • ab110161, at a 1/50 dilution, staining GCHFR in paraffin embedded Human colon carcinoma tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of the immunizing peptide.

References for Anti-GCHFR antibody (ab110161)

ab110161 has not yet been referenced specifically in any publications.

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