Overview

  • Product name
  • Description
    Rabbit polyclonal to GCNT2
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence, corresponding to amino acids 181-293 of Human GCNT2 Isoforms A and C (Q8N0V5, Q8NFS9).

  • Positive control
    • Human testis tissue; RT 4, U 51 MG, Human liver and tonsil lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab121888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Relevance
    GCNT2 is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase that converts linear into branched poly-N-acetyllactosaminoglycans and is responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding 3 different isoforms have been described.
  • Cellular localization
    Golgi apparatus membrane.
  • Database links
  • Alternative names
    • bA360O19.2 antibody
    • bA421M1.1 antibody
    • Beta 1 6 N acetylglucosaminyltransferase 2 antibody
    • CCAT antibody
    • GCNT 2 antibody
    • GCNT2C antibody
    • GCNT5 antibody
    • Glucosaminyl (N acetyl) transferase 2 I branching enzyme (I blood group) antibody
    • Glucosaminyl (N acetyl) transferase 2 I branching enzyme antibody
    • I beta 1 6 N acetylglucosaminyltransferase antibody
    • I branching beta 1 6 acetylglucosaminyltransferase antibody
    • I branching enzyme antibody
    • IGNT antibody
    • II antibody
    • Ii blood group antibody
    • MGC163396 antibody
    • N acetylglucosaminyltransferase antibody
    • N acetyllactosaminide beta 1 6 N acetylglucosaminyltransferase antibody
    • N acetyllactosaminide beta 1,6 N acetylglucosaminyl transferase antibody
    • NACGT1 antibody
    • NAGCT1 antibody
    • ULG3 antibody
    see all

Images

  • ab121888 at 1/300 dilution staining GCNT2 in Paraffin-embedded Human Testis tissue by Immunohistochemistry.
  • All lanes : Anti-GCNT2 antibody (ab121888) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

References

ab121888 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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