Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab73288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 51 kDa).

Target

  • RelevanceGDF6 (Growth/differentiation factor 6) is expressed in hypertrophic chondrocytes during embryonic development of long bones and is required for normal formation of bones and joints in the limbs, skull, and axial skeleton. It plays a key role in establishing boundaries between skeletal elements during development. The functional form of GDF6 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains obtained by proteolytic processing of a biologically inactive precursor protein.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • bmp 13 antibody
    • bmp13 antibody
    • Cartilage Derived Morphogenetic Protein 2 antibody
    • cdmp 2 antibody
    • CDMP2 antibody
    • gdf 6 antibody
    • GDF16 antibody
    • Growth differentiation factor 6 antibody
    • Growth/differentiation factor 16 antibody
    • Growth/differentiation factor 6 antibody
    • KFM antibody
    • KFS antibody
    • KFS1 antibody
    • KFSL antibody
    • Klip Feil malformation antibody
    • Klippel Feil malformation antibody
    • Klippel Feil syndrome antibody
    • LCA17 antibody
    • MCOP4 antibody
    • MCOPCB6 antibody
    • SCDO4 antibody
    • SGM1 antibody
    see all

Anti-GDF6 antibody images

  • Lane 1 : Anti-GDF6 antibody (ab73288) at 0.5 µg/ml
    Lane 2 : Anti-GDF6 antibody (ab73288) at 1 µg/ml

    Lane 1 : SK-N-SH lysate
    Lane 2 : SK-N-SH lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 51 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-GDF6 antibody (ab73288) at 1 µg/ml

    Lane 1 : Recombinant Human GDF6 protein (ab50230) at 0.1 µg
    Lane 2 : Recombinant Human GDF6 protein (ab50230) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

References for Anti-GDF6 antibody (ab73288)

ab73288 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"