Overview

  • Product name
    Anti-GDF6 antibody - N-terminal
    See all GDF6 primary antibodies
  • Description
    Rabbit polyclonal to GDF6 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: Flow Cyt, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human GDF6 aa 38-67 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q6KF10

  • Positive control
    • Mouse liver tissue lysate; Human testis tissue; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab170532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/50 - 1/100. Predicted molecular weight: 51 kDa.

Target

  • Relevance
    GDF6 (Growth/differentiation factor 6) is expressed in hypertrophic chondrocytes during embryonic development of long bones and is required for normal formation of bones and joints in the limbs, skull, and axial skeleton. It plays a key role in establishing boundaries between skeletal elements during development. The functional form of GDF6 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains obtained by proteolytic processing of a biologically inactive precursor protein.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • bmp 13 antibody
    • bmp13 antibody
    • Cartilage Derived Morphogenetic Protein 2 antibody
    • cdmp 2 antibody
    • CDMP2 antibody
    • gdf 6 antibody
    • GDF16 antibody
    • Growth differentiation factor 6 antibody
    • Growth/differentiation factor 16 antibody
    • Growth/differentiation factor 6 antibody
    • KFM antibody
    • KFS antibody
    • KFS1 antibody
    • KFSL antibody
    • Klip Feil malformation antibody
    • Klippel Feil malformation antibody
    • Klippel Feil syndrome antibody
    • LCA17 antibody
    • MCOP4 antibody
    • MCOPCB6 antibody
    • SCDO4 antibody
    • SGM1 antibody
    see all

Images

  • Anti-GDF6 antibody - N-terminal (ab170532) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 51 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling GDF6 with ab170532 at 1/50 dilution followed by peroxidase conjugation of the secondary antibody and DAB detection.

  • Flow cytometric analysis of HeLa cells labeling GDF6 with ab170532 at 1/10 dilution (right histogram), compared to a negative control cell (left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis.

References

ab170532 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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