Anti-GDNF Receptor alpha 2 antibody (ab19146)

Overview

  • Product nameAnti-GDNF Receptor alpha 2 antibody
    See all GDNF Receptor alpha 2 primary antibodies
  • Description
    Rabbit polyclonal to GDNF Receptor alpha 2
  • SpecificityThis antibody recognizes human, mouse, and rat GFR alpha 2.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    RVEKTPSLPDDLSDS

    , corresponding to amino acids 377-391 of Human GFR alpha 2.

  • Positive control
    • Whole cell lysate of HeLa cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesThis antibody was Purified by DEAE column.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab19146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).

Target

  • FunctionReceptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
    Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
  • Tissue specificityIsoform 1 is found in both brain and placenta.
  • Sequence similaritiesBelongs to the GDNFR family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GDNF family receptor alpha 2 antibody
    • GDNF family receptor alpha-2 antibody
    • GDNF receptor alpha-2 antibody
    • GDNF receptor beta antibody
    • GDNFR beta antibody
    • GDNFR-alpha-2 antibody
    • GDNFR-beta antibody
    • GDNFRB antibody
    • GFR alpha 2 antibody
    • GFR-alpha-2 antibody
    • GFRA 2 antibody
    • Gfra2 antibody
    • GFRA2_HUMAN antibody
    • Glial cell line derived neurotrophic factor family receptor alpha2b antibody
    • Glial cell line derived neurotrophic factor receptor beta antibody
    • Neurturin receptor alpha antibody
    • NRTNR alpha antibody
    • NRTNR-alpha antibody
    • NTNR alpha antibody
    • NTNR-alpha antibody
    • NTNRA antibody
    • PI linked cell surface accessory protein antibody
    • PI linked cell-surface accessory protein antibody
    • RET ligand 2 antibody
    • RETL 2 antibody
    • RETL2 antibody
    • TGF beta related neurotrophic factor receptor 2 antibody
    • TGF-beta-related neurotrophic factor receptor 2 antibody
    • TRN receptor GPI anchored antibody
    • TRNR 2 antibody
    • TRNR2 antibody
    see all

References for Anti-GDNF Receptor alpha 2 antibody (ab19146)

ab19146 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"