Anti-GDNF Receptor alpha 2 antibody (ab6170)

Overview

  • Product name
    Anti-GDNF Receptor alpha 2 antibody
    See all GDNF Receptor alpha 2 primary antibodies
  • Description
    Rabbit polyclonal to GDNF Receptor alpha 2
  • Specificity
    Specific to GFR alpha 2. No reaction with its homologues.
  • Tested applications
    Suitable for: IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    PRVEKTPSLPDDLSD

    conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 376-390 of Rat GDNF family Receptor alpha 2.

  • General notes
    This antibody stains large neurons in the rat dorsal root ganglia. It has also proven useful for western blot of rat brain.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab6170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
WB
  • Application notes
    Immunohistochemistry: 1/1,000
    Western Blot: 1/500-1,000
    Immunoblot: Not tested.
    1 site ELISA: Not tested.
    Biological Inhibition: Not tested.
  • Target

    • Function
      Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
      Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
    • Tissue specificity
      Isoform 1 is found in both brain and placenta.
    • Sequence similarities
      Belongs to the GDNFR family.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • GDNF family receptor alpha 2 antibody
      • GDNF family receptor alpha-2 antibody
      • GDNF receptor alpha-2 antibody
      • GDNF receptor beta antibody
      • GDNFR beta antibody
      • GDNFR-alpha-2 antibody
      • GDNFR-beta antibody
      • GDNFRB antibody
      • GFR alpha 2 antibody
      • GFR-alpha-2 antibody
      • GFRA 2 antibody
      • Gfra2 antibody
      • GFRA2_HUMAN antibody
      • Glial cell line derived neurotrophic factor family receptor alpha2b antibody
      • Glial cell line derived neurotrophic factor receptor beta antibody
      • Neurturin receptor alpha antibody
      • NRTNR alpha antibody
      • NRTNR-alpha antibody
      • NTNR alpha antibody
      • NTNR-alpha antibody
      • NTNRA antibody
      • PI linked cell surface accessory protein antibody
      • PI linked cell-surface accessory protein antibody
      • RET ligand 2 antibody
      • RETL 2 antibody
      • RETL2 antibody
      • TGF beta related neurotrophic factor receptor 2 antibody
      • TGF-beta-related neurotrophic factor receptor 2 antibody
      • TRN receptor GPI anchored antibody
      • TRNR 2 antibody
      • TRNR2 antibody
      see all

    References

    ab6170 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Thank you for your enquiry. In answer to your questions. We state "centrifuge to remove any insoluble material" on the product datasheet because this product is whole serum and therefore prior to use it is a good idea to centrifuge the sera to remo...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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