Anti-GDNF Receptor alpha 2 antibody (ab6170)

Overview

  • Product nameAnti-GDNF Receptor alpha 2 antibody
    See all GDNF Receptor alpha 2 primary antibodies
  • Description
    Rabbit polyclonal to GDNF Receptor alpha 2
  • SpecificitySpecific to GFR alpha 2. No reaction with its homologues.
  • Tested applicationsSuitable for: IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    PRVEKTPSLPDDLSD

    conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 376-390 of Rat GDNF family Receptor alpha 2.

  • General notesThis antibody stains large neurons in the rat dorsal root ganglia. It has also proven useful for western blot of rat brain.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • PurityWhole antiserum
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab6170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
WB
  • Application notesImmunohistochemistry: 1/1,000
    Western Blot: 1/500-1,000
    Immunoblot: Not tested.
    1 site ELISA: Not tested.
    Biological Inhibition: Not tested.
  • Target

    • FunctionReceptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
      Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
    • Tissue specificityIsoform 1 is found in both brain and placenta.
    • Sequence similaritiesBelongs to the GDNFR family.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • GDNF family receptor alpha 2 antibody
      • GDNF family receptor alpha-2 antibody
      • GDNF receptor alpha-2 antibody
      • GDNF receptor beta antibody
      • GDNFR beta antibody
      • GDNFR-alpha-2 antibody
      • GDNFR-beta antibody
      • GDNFRB antibody
      • GFR alpha 2 antibody
      • GFR-alpha-2 antibody
      • GFRA 2 antibody
      • Gfra2 antibody
      • GFRA2_HUMAN antibody
      • Glial cell line derived neurotrophic factor family receptor alpha2b antibody
      • Glial cell line derived neurotrophic factor receptor beta antibody
      • Neurturin receptor alpha antibody
      • NRTNR alpha antibody
      • NRTNR-alpha antibody
      • NTNR alpha antibody
      • NTNR-alpha antibody
      • NTNRA antibody
      • PI linked cell surface accessory protein antibody
      • PI linked cell-surface accessory protein antibody
      • RET ligand 2 antibody
      • RETL 2 antibody
      • RETL2 antibody
      • TGF beta related neurotrophic factor receptor 2 antibody
      • TGF-beta-related neurotrophic factor receptor 2 antibody
      • TRN receptor GPI anchored antibody
      • TRNR 2 antibody
      • TRNR2 antibody
      see all

    References for Anti-GDNF Receptor alpha 2 antibody (ab6170)

    ab6170 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. In answer to your questions. We state "centrifuge to remove any insoluble material" on the product datasheet because this product is whole serum and therefore prior to use it is a good idea to centrifuge the sera to remo...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"