Overview

  • Product name
  • Description
    Rabbit polyclonal to Gemin 2
  • Tested applications
    Suitable for: WB, ELISA, IHC-P, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide from the C terminus of Human Gemin 2, conjugated to KLH.

  • Positive control
    • Human tonsil, thymus or colon nerve tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab117639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 31 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.
ICC Use a concentration of 4 µg/ml.

Target

  • Function
    The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
  • Sequence similarities
    Belongs to the gemin-2 family.
  • Cellular localization
    Nucleus > gem. Cytoplasm. Localized in subnuclear structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs. Also found in the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Component of gems 2 antibody
    • Gem (nuclear organelle) associated protein 2 antibody
    • Gem associated protein 2 antibody
    • GEMI2_HUMAN antibody
    • Gemin-2 antibody
    • gemin2 antibody
    • SIP 1 antibody
    • SIP-1 antibody
    • SIP1 antibody
    • SIP1 delta antibody
    • SIP1-delta antibody
    • SMN interacting protein 1 antibody
    • SMN interacting protein 1 delta antibody
    • SMN-interacting protein 1 antibody
    • Survival interacting protein 1 antibody
    • Survival of motor neuron protein interacting protein 1 antibody
    • Survival of motor neuron protein-interacting protein 1 antibody
    see all

Images

  • Human Colon Nerve, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117639 at 5µg/ml.
  • Human thymus, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117639 at 5µg/ml.
  • Human tonsil, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117639 at 5µg/ml.

References

ab117639 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab117639.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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