Application notesThis antibody gave a positive result in ELISA against the immunizing peptide (ab33357).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceThe protein encoded by this gene is a component of the core SMN complex, which is required for pre-mRNA splicing in the nucleus. The encoded protein is found in the nucleoplasm, in nuclear "gems" (Gemini of Cajal bodies) and in the cytoplasm.