Overview

  • Product nameAnti-Gemin 8 antibody [1F8]
    See all Gemin 8 primary antibodies
  • Description
    Mouse monoclonal [1F8] to Gemin 8
  • Tested applicationsSuitable for: WB, IP, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fusion protein (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab46778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 29 kDa.
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

Target

  • RelevanceGemin 8 forms a large macromolecular complex which includes other gemin proteins, SMN (survival motor neuron) protein and Unrip. This complex is required for assembly of small nuclear ribonucleoproteins (snRNPs) from Sm proteins and snRNAs. Gemin 8 mediates the binding of SMN with gemin 6 and gemin 7.
  • Cellular localizationCytoplasmic and Nuclear
  • Database links
  • Alternative names
    • FAM51A1 antibody
    • FLJ20514 antibody
    • FLJ43072 antibody
    • gem (nuclear organelle) associated protein 8 antibody

References for Anti-Gemin 8 antibody [1F8] (ab46778)

This product has been referenced in:
  • Carissimi C  et al. Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. J Biol Chem 281:8126-34 (2006). Read more (PubMed: 16434402) »
  • Carissimi C  et al. Gemin8 is required for the architecture and function of the survival motor neuron complex. J Biol Chem 281:37009-16 (2006). Read more (PubMed: 17023415) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"