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Product Name
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GFAP antibody [GA-5] - Astrocyte Marker, prediluted
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See all GFAP antibodies (29)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [GA-5] to GFAP - Astrocyte Marker, prediluted
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Immunogen
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GFAP isolated from porcine spinal cord.
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Reacts with
(species key)
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Hu, Rat, Chk, Pig
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Specificity
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This antibody reacts with human GFAP.
It shows no cross-reaction with other intermediate filaments.
Anti-GFAP stains astrocytes, ependymal cells and corresponding tumors.
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
This antibody is ready to use.
For best results use heat mediated antigen retrieval, this can enhance staining if tissues are over-fixed.
Do not use enzymatic mediated antigen retrieval.
We recommend incubating sections with the antibody for 30-60 minutes at room temperature.
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Positive control
(see definition)
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Normal brain or astrocytoma
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Cellular localization
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Cytoplasmic
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Research areas
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Stem Cells >> Neural Stem Cells >> Glial Restricted Lineage >> Astrocyte
Tags & Cell Markers >> Cell Type Markers >> Neuroscience Markers >> Glial
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Intermediate Filaments >> Class II >> GFAP
Neuroscience >> Cell Type Marker >> Glia marker >> Astrocyte marker
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Intermediate Filaments
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Relevance
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Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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GA-5
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Isotype
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IgG1
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: PBS, Carrier protein, pH 7.3 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Storage instructions
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Store at +4°C. Do not freeze.
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Notes
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GFAP is Glial Fibrillary Acidic Protein
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GFAP antibody [GA-5] - Astrocyte Marker, prediluted is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to GFAP
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GFAP antibody [GA-5] - Astrocyte Marker, prediluted - more information
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