Overview

  • Product name
  • Description
    Rabbit polyclonal to GGPS1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 105-300 of Human GGPS1 (Uniprot ID: O95749).

  • Positive control
    • PC3 and SK-N-SH whole cell lysates; Human BT483 xenograft tissue.
  • General notes
    Keep as a concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/20000. Predicted molecular weight: 35 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
  • Tissue specificity
    Abundantly expressed in testis. Found in other tissues to a lower extent.
  • Pathway
    Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
    Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
    Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
  • Sequence similarities
    Belongs to the FPP/GGPP synthase family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • (2E antibody
    • 6E)-farnesyl diphosphate synthase antibody
    • Dimethylallyltranstransferase antibody
    • Farnesyl diphosphate synthase antibody
    • Farnesyltranstransferase antibody
    • Geranylgeranyl diphosphate synthase 1 antibody
    • Geranylgeranyl diphosphate synthase antibody
    • Geranylgeranyl pyrophosphate synthase antibody
    • Geranylgeranyl pyrophosphate synthetase antibody
    • Geranyltranstransferase antibody
    • GGPP synthase antibody
    • GGPP synthetase antibody
    • GGPPS antibody
    • GGPPS_HUMAN antibody
    • GGPPS1 antibody
    • GGPPSase antibody
    • GGPS1 antibody
    • OTTHUMP00000036073 antibody
    • OTTHUMP00000216161 antibody
    • OTTHUMP00000216163 antibody
    • OTTHUMP00000216164 antibody
    see all

Images

  • All lanes : Anti-GGPS1 antibody (ab155584) at 1/10000 dilution

    Lane 1 : PC3 whole cell lysate
    Lane 2 : SK-N-SH whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 35 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human BT483 xenograft tissue labeling GGPS1 with ab155584 at 1/500 dilution.

References

ab155584 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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