Overview

  • Product name
    Anti-GGPS1 antibody [EPR9682]
    See all GGPS1 primary antibodies
  • Description
    Rabbit monoclonal [EPR9682] to GGPS1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human GGPS1 (UniProt: O95749).

  • Positive control
    • K562, HeLa, 293T and Jurkat cell lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab167168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 35 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function
      Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
    • Tissue specificity
      Abundantly expressed in testis. Found in other tissues to a lower extent.
    • Pathway
      Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
      Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
      Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
    • Sequence similarities
      Belongs to the FPP/GGPP synthase family.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • (2E antibody
      • 6E)-farnesyl diphosphate synthase antibody
      • Dimethylallyltranstransferase antibody
      • Farnesyl diphosphate synthase antibody
      • Farnesyltranstransferase antibody
      • Geranylgeranyl diphosphate synthase 1 antibody
      • Geranylgeranyl diphosphate synthase antibody
      • Geranylgeranyl pyrophosphate synthase antibody
      • Geranylgeranyl pyrophosphate synthetase antibody
      • Geranyltranstransferase antibody
      • GGPP synthase antibody
      • GGPP synthetase antibody
      • GGPPS antibody
      • GGPPS_HUMAN antibody
      • GGPPS1 antibody
      • GGPPSase antibody
      • GGPS1 antibody
      • OTTHUMP00000036073 antibody
      • OTTHUMP00000216161 antibody
      • OTTHUMP00000216163 antibody
      • OTTHUMP00000216164 antibody
      see all

    Images

    • All lanes : Anti-GGPS1 antibody [EPR9682] (ab167168) at 1/1000 dilution

      Lane 1 : K562 cell lysates
      Lane 2 : HeLa cell lysates
      Lane 3 : 293T cell lysates
      Lane 4 : Jurkat cell lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 35 kDa

    References

    This product has been referenced in:
    • Chen GP  et al. Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process. J Diabetes Res 2015:379287 (2015). WB . Read more (PubMed: 25918730) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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