Overview

  • Product name
    Anti-GIMAP3P antibody
  • Description
    Rabbit polyclonal to GIMAP3P
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide derived from C terminal domain of mouse GIMAP3P protein

Properties

Applications

Our Abpromise guarantee covers the use of ab76757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/1000 - 1/5000. Predicted molecular weight: 34 kDa.

Target

  • Relevance
    GIMAP3p is a murine mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The IAN/GIMAP family consists of GTP-binding proteins that share a unique primary structure and whose expression is finely regulated by T-cell receptor signals. Recent studies have shown that IAN/GIMAP family proteins crucially regulate the survival of T cells during development, selection and homeostasis, and are possibly linked to the onset of T-lymphopenia, leukemia and autoimmunity. IAN/GIMAP family proteins might also take part in mitochondrial regulation of lymphocyte apoptosis by interacting with Bcl-2 family proteins. The human GIMAP (GTPase of the immunity-associated protein) gene family includes seven functional members residing on (human) chromosome 7q36.1 and one pseudogene (hGIMAP3).
  • Cellular localization
    Mitochondrion outer membrane; Single-pass type IV membrane protein
  • Database links
  • Alternative names
    • 2010110D23Rik antibody
    • GIMAP 3 antibody
    • GIMAP3 antibody
    • Gimap5 antibody
    • GTPase IMAP family member 3 antibody
    • GTPase of the immune associated protein 3 antibody
    • GTPase, IMAP family member 3 pseudogene antibody
    • Ian4 antibody
    • Immune associated nucleotide 4 antibody
    • Immunity associated nucleotide 4 protein antibody
    see all

References

ab76757 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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