Anti-GIMAP4 antibody [EPR5230(B)] (ab124944)

Overview

  • Product nameAnti-GIMAP4 antibody [EPR5230(B)]
    See all GIMAP4 primary antibodies
  • Description
    Rabbit monoclonal [EPR5230(B)] to GIMAP4
  • Tested applicationsSuitable for: WB, IP, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to N terminal residues of Human GIMAP4.

  • Positive control
    • Human tonsil tissue; Human tonsil lysate and peripheral blood leukocytes lysate
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab124944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 38 kDa.
IP 1/10 - 1/100.
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/250.

Target

  • FunctionExhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.
  • Tissue specificityHighly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
  • Sequence similaritiesBelongs to the IAN GTP-binding protein family.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ11110 antibody
    • GIMA4_HUMAN antibody
    • Gimap4 antibody
    • GTPase IMAP family member 4 antibody
    • GTPase IMAP family member 4 antibody
    • hIAN1 antibody
    • HIMAP4 antibody
    • Human immune associated nucleotide 1 antibody
    • IAN-1 antibody
    • IAN1 antibody
    • IMAP4 antibody
    • Immunity associated nucleotide 1 protein antibody
    • Immunity associated protein 4 antibody
    • Immunity-associated nucleotide 1 protein antibody
    • Immunity-associated protein 4 antibody
    • MSTP062 antibody
    see all

Anti-GIMAP4 antibody [EPR5230(B)] images

  • All lanes : Anti-GIMAP4 antibody [EPR5230(B)] (ab124944) at 1/1000 dilution

    Lane 1 : Human tonsil lysate
    Lane 2 : Peripheral blood leukocytes lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    standard HRP labelled goat anti-rabbit at 1/2000 dilution

    Predicted band size : 38 kDa
  • ab124944, at a 1/500 dilution, staining GIMAP4 in paraffin embedded Human tonsil tissue by Immunohistochemistry.

References for Anti-GIMAP4 antibody [EPR5230(B)] (ab124944)

ab124944 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"