Overview

  • Product nameAnti-GIRK1 antibody
    See all GIRK1 primary antibodies
  • Description
    Rabbit polyclonal to GIRK1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Guinea pig
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 248-501 of Human GIRK1.

  • Positive control
    • A431, H1299, HeLa whole cells lysate, DU145 xenograft

Properties

Applications

Our Abpromise guarantee covers the use of ab96168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/500.

Target

  • FunctionThis potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
  • Sequence similaritiesBelongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein activated inward rectifier potassium channel 1 antibody
    • G protein-activated inward rectifier potassium channel 1 antibody
    • GIRK-1 antibody
    • GIRK1 antibody
    • Inward rectifier K(+) channel Kir3.1 antibody
    • Inwardly rectifying potassium channel KIR3.1 antibody
    • inwardly rectifying subfamily J member 3 antibody
    • IRK3 antibody
    • IRK3_HUMAN antibody
    • Kcnf3 antibody
    • Kcnj3 antibody
    • KGA antibody
    • KGB1 antibody
    • Kir3.1 antibody
    • Potassium channel antibody
    • Potassium channel, inwardly rectifying subfamily J member 3 antibody
    • Potassium inwardly-rectifying channel, subfamily J, member 3 antibody
    see all

Anti-GIRK1 antibody images

  • All lanes : Anti-GIRK1 antibody (ab96168) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 57 kDa
  • Immunohistochemical analysis of paraffin-embedded DU145 xenograft, using ab96168 at 1:100 dilution.

References for Anti-GIRK1 antibody (ab96168)

ab96168 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"