Overview

  • Product name
    Anti-GLMN antibody - C-terminal
    See all GLMN primary antibodies
  • Description
    Rabbit polyclonal to GLMN - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: Flow Cyt, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human GLMN aa 505-533 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q92990

  • Positive control
    • MDA-MB231 and HepG2 cell line lysates; K562 cells; Human bladder carcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab170776 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 68 kDa.

Target

  • Function
    Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production.
  • Tissue specificity
    Ubiquitous.
  • Involvement in disease
    Glomuvenous malformations
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Information by UniProt
  • Database links
  • Alternative names
    • FAP antibody
    • FAP48 antibody
    • FAP68 antibody
    • FK506 binding protein associated protein antibody
    • FK506-binding protein-associated protein antibody
    • FKBP associated protein antibody
    • FKBP-associated protein antibody
    • FKBP-associated protein, 48-KD antibody
    • FKBP-associated protein, 68-KD antibody
    • FKBPAP antibody
    • GLML antibody
    • Glmn antibody
    • GLMN_HUMAN antibody
    • Glomulin antibody
    • glomulin, FKBP associated protein antibody
    • GVM antibody
    • VMGLOM antibody
    see all

Images

  • All lanes : Anti-GLMN antibody - C-terminal (ab170776) at 1/100 dilution

    Lane 1 : MDA-MB231 cell line lysate
    Lane 2 : HepG2 cell line lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 68 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human bladder carcinoma tissue labeling GLMN with ab170776 at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Flow cytometric analysis of K562 cells labeling GLMN with ab170776 at 1/10 dilution (right histogram) compared to negative control cells (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References

ab170776 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab170776.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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