Overview

  • Product name
    Anti-GLRA4 antibody
  • Description
    Rabbit polyclonal to GLRA4
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: IRLRRRQRRQ RLEEDIIQES RFYFRGYGLG HCLQARDGGP MEGSGIYSPQ PPAPLLREGE TTRKLYVD, corresponding to C terminal amino acids 350-417 of Human GLRA4.

  • Positive control
    • Human adrenal gland tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab122877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
  • Sequence similarities
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA4 sub-subfamily.
  • Cellular localization
    Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glra4 antibody
    • GLRA4_HUMAN antibody
    • Glycine receptor subunit alpha-4 antibody
    • Glycine receptor, alpha 4 antibody

Images

  • ab122877 at 1/50 dilution staining GLRA4 in paraffin-embedded Human adrenal gland tissue by Immunohistochemistry.

References

ab122877 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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